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Showing result 1 - 5 of 42 swedish dissertations matching the above criteria.

2. 1. Management control and strategy : a case study of pharmaceutical drug development

   Author : Fredrika Berglund; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Management control systems; Tight control; Loose control; Interactive control; Diagnostic control; Budget; Portfolio management; Project management; Goals and Objectives systems; Business strategy; Research Development; Pharmaceutical; Computer science; Datavetenskap; Economic Information Systems; Ekonomiska informationssystem;

   Abstract : How are formal management controls designed and used in research & development (R&D)? The purpose of this study is to explain how such systems are designed and used in formulating and implementing strategies in a pharmaceutical product development organisation. The study uses a contingency approach to investigate how the control system is adjusted to the business strategy of the firm. READ MORE

4. 2. Ligand-based Methods for Data Management and Modelling

   Author : Jonathan Alvarsson; Jarl E. S. Wikberg; Ola Spjuth; Claes Andersson; Martin Eklund; John P. Overington; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; QSAR; ligand-based drug discovery; bioclipse; information system; cheminformatics; bioinformatics; Farmaceutisk farmakologi; Pharmaceutical Pharmacology; Bioinformatik; Bioinformatics;

   Abstract : Drug discovery is a complicated and expensive process in the billion dollar range. One way of making the drug development process more efficient is better information handling, modelling and visualisation. The majority of todays drugs are small molecules, which interact with drug targets to cause an effect. READ MORE

5. 3. Pharmaceutical care in coronary heart disease

   Author : Malin Johansson Östbring; Göran Petersson; Lina Hellström; Tommy Eriksson; Hughes Carmel; Linnéuniversitetet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmaceutical care; patient experience; medication adherence; medicine management; medication review; motivational interviewing; coronary heart disease; secondary prevention; low-density lipoprotein cholesterol; cardiac rehabilitation; multi-professional collaboration; drug-related problems; pragmatic clinical trial; randomized controlled trial; qualitative analysis; process evaluation; Biomedical Sciences; Biomedicinsk vetenskap; Health and Caring Sciences; Hälsovetenskap;

   Abstract : Background: In coronary heart disease (CHD), pharmaceutical care implies that health care professionals cooperate with the patient to optimize drug therapy primarily for secondary prevention. Low adherence and discontinuation of drugs are common among patients with CHD, and this is associated with increased morbidity and mortality. READ MORE

6. 4. Translational Aspects of Blood-Brain Barrier Transport and Brain Distribution of Drugs in Health and Disease

   Author : Sofia Gustafsson; Margareta Hammarlund-Udenaes; Stina Syvänen; Irena Loryan; Danica Stanimirovic; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Neurovascular unit; Pharmacokinetics; Neurodegenerative disease; Drug transport; Brain tissue binding; Positron emission tomography; Brain regions; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : A high unmet medical need in the area of CNS diseases coincides with high failure rates in CNS drug development. Efficient treatment of CNS disease is constrained by limited entrance of drugs into the brain owing to the blood-brain barrier (BBB), which separates brain from blood. READ MORE

7. 5. Exploring the Shadows of Project Management

   Author : Jan Wickenberg; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; informal organization; project management framework; project management; organization theory; formal organization; shadow system;

   Abstract : The project has become a preferred way of organizing work. Two major reasons for this trend are demands for increased market responsiveness and the empowering of workgroups in order to improve employee commitment. READ MORE