Search for dissertations about: "pharmaceutical powder"

Showing result 1 - 5 of 38 swedish dissertations containing the words pharmaceutical powder.

  2. 1. Powder mechanics and dispersion properties of adhesive mixtures for dry powder inhalers : Conceptualized as a blend state model

    Author : Jonas Rudén; Göran Alderborn; Göran Frenning; Tobias Bramer; Kyrre Thalberg; Regina Scherliess; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inhalation; Dry Powder Inhaler; adhesive mixture; aerosols; powder mechanics; dispersibility; aerosolization; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Inhaled medicines is a therapy that dates back several thousands of years. Nowadays, using various types of inhaler devices to deliver active pharmaceutical ingredients (APIs) to treat respiratory diseases has become common practice. READ MORE

  4. 2. Process-induced disorder of pharmaceutical materials : Mechanisms and quantification of disorder

    Author : Samaneh Pazesh; Göran Alderborn; Jonas Berggren; Niklas Sandler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Milling; Comminution; Powder flow; Amorphisation; Raman spectroscopy; Atomic force microscopy; Plastic stiffness; Elastic stiffness; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : One of the most important prerequisites in the drug development is to attain a reproducible and robust product in terms of its nature, and its chemical and physical properties. This can be challenging, since the crystalline form of drugs and excipients can be directly transformed into the amorphous one during normal pharmaceutical processing, referred to as process-induced amorphisation or process-induced disorder. READ MORE

  5. 3. Preparation of Pharmaceutical Powders using Supercritical Fluid Technology : Pharmaceutical Applications and Physicochemical Characterisation of Powders

    Author : Sitaram Velaga; Johan Carlfors; Kristiina Järvinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Supercritical fluid; Gas Anti-Solvent; SEDS; Crystallisation; Particle design; Polymorphs; Dry powder inhalation; Solid-state behaviour; Therapeutic proteins; Precipitation; Stability; Recombinant human growth hormone hGH ; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Abstract : The main aim of the thesis was to explore the potential of supercritical fluid (SF) techniques in the field of drug delivery. In particular, the relatively recently developed solution-enhanced dispersion by supercritical fluids (SEDS) technology has been employed in the preparation of particles/powders. READ MORE

  6. 4. Solid state characterisation and compaction behaviour of pharmaceutical materials

    Author : Christina Gustafsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Solid-state; Tablet; Thermal analysis; Cellulose; Spectroscopy; NMR; NIR; FT-IR; Crystallinity; MVDA; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Abstract : In this thesis, factors important in tableting operations and for tablet properties have been studied and characterised by different spectroscopic techniques as well as by some more conventionally used particle characterisation techniques. The spectroscopic techniques solid-state NMR, FT-IR and NIR spectroscopy, proved to be valuable tools in the estimation of particle and tablet properties, offering both specificity and sensitivity in the measurements. READ MORE

  7. 5. Terahertz sensing for pharmaceutical applications

    Author : Anis Moradikouchi; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; frequency domain spectroscopy; terahertz sensing; multivariate analysis; Pharmaceutical; radar; porosity; powders; API content; tablets; powder flow characterization; tablet density;

    Abstract : Pharmaceutical tablets are manufactured through the compaction of powder blends or granules in batch or continuous processes. In continuous manufacturing, real-time assurance of quality becomes essential to ensure that the final product meets the quality standards approved by manufacturers and regulatory authorities. READ MORE