Search for dissertations about: "pharmacodynamics"

Showing result 1 - 5 of 96 swedish dissertations containing the word pharmacodynamics.

  1. 1. Pharmacokinetics and pharmacodynamics of pentoxifylline and metabolites

    University dissertation from Lund University, Faculty of Medicine

    Author : Marie V Magnusson; Lunds universitet.; Lund University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; Pentoxifylline; metabolites; pharmacodynamics;

    Abstract : Pentoxifylline is a haemorheologic drug with complex pharmacokinetics and pharmacodynamics due to both reversible metabolism and the formation of active metabolites. In humans, pentoxifylline is metabolised to at least seven phase 1 metabolites (M1-M7). READ MORE

  2. 2. Clinical pharmacokinetics and pharmacodynamics of antimalarial combination therapy

    University dissertation from Lund University, Faculty of Medicine

    Author : Sofia Friberg Hietala; Göteborgs universitet.; Gothenburg University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; antimalarials; artemisinins;

    Abstract : In the face of growing drug resistance, the World Health Organization (WHO) has issued recommendations strongly encouraging the use of combination therapies to combat uncomplicated malaria. Amongst the most effective treatments are those combining an artemisinin derivative with a longer acting component such as amodiaquine, lumefantrine or piperaquine. READ MORE

  3. 3. Pharmacodynamics of Enzyme Induction and its Consequences for Substrate Elimination

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mats O. Magnusson; Uppsala universitet.; [2007]
    Keywords : Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Enzyme induction; Time course; Turnover model; Mechanism-based; Modelling; NONMEM; Farmakokinetik Farmakoterapi;

    Abstract : Enzyme induction is a process whereby a molecule enhances the expression of enzymes. If the affected enzymes are involved in the elimination of a drug, this may result in a drug interaction. Induction is therefore of major concern during drug development and in clinical practice. READ MORE

  4. 4. Premedication for intubation in newborn infants; pain assessment, pharmacokinetics and pharmacodynamics

    University dissertation from Division of Paediatrics, Department of clinical Sciences, Lund University, Sweden

    Author : Elisabeth Norman; Lunds universitet.; Lund University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Premedication; pain; premature; newborn; aEEG; randomized controlled trial; thiopental; morphine; remifentanil; rapid sequence induction; ibntubation; pharmacokinetics; pharmacodynamics;

    Abstract : Popular Abstract in Swedish För tidigt födda barn genomgår intensivvård under en period när de är väldigt sårbara pga instabil cirkulation och ett omoget centralt nervsystem under snabb utveckling. Tillräcklig behandling av smärta är av största betydelse eftersom stark smärtupplevelse kan medföra skadliga omedelbara kroppsreaktioner, men också neurologiska och neuropsykologiska seneffekter. READ MORE

  5. 5. In vitro Pharmacodynamics of Antifungal Agents in the Treatment of Candida Infections

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anders Lignell; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amphotericin B; antagonism; Candida; human serum; inhibition; interaction; in vitro; kinetic model; pharmacodynamics; pharmacokinetics; posaconazole; protein binding; voriconazole; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

    Abstract : Pharmacodynamic studies are important for the optimal use of antimicrobial agents. Combination antifungal therapy may be one method to improve outcome in invasive Candida infections. READ MORE