Search for dissertations about: "pharmacology thesis 2012"
Showing result 1 - 5 of 11 swedish dissertations containing the words pharmacology thesis 2012.
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1. On the Prediction of Warfarin Dose
Abstract : Warfarin is one of the most widely used anticoagulants in the world. Treatment is complicated by a large inter-individual variation in the dose needed to reach adequate levels of anticoagulation i.e. INR 2. READ MORE
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2. Cannabinoids as modulators of cancer cell viability, neuronal differentiation, and embryonal development
Abstract : Cannabinoids (CBs) are compounds that activate the CB1 and CB2 receptors. CB receptors mediate many different physiological functions, and cannabinoids have been reported to decrease tumor cell viability, proliferation, migration, as well as to modulate metastasis. READ MORE
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3. Clinical Pharmacogenetics of Olanzapine : with Focus on FMO Gene Polymorphisms
Abstract : Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used antipsychotic drug for schizophrenia treatment. The pharmacokinetics of OLA display large inter-individual variation leading to multiple-fold differences in drug exposure between patients at a given dose. READ MORE
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4. Studies of Retroviral Reverse Transcriptase and Flaviviral Protease Enzymes as Antiviral Drug Targets : Applications in Antiviral Drug Discovery & Therapy
Abstract : Viruses are a major threat to humans due to their unique adaptability, evolvability and capability to control their hosts as parasites and genetic elements. HIV/AIDS is the third largest cause of death by infectious diseases in the world, and drug resistance due to the viral mutations is still the leading cause of treatment failure. READ MORE
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5. Dietary fatty acids increase the absorption of toxic substances and drugs by modifying different absorption pathways in the intestinal epithelium
Abstract : Dietary fatty acids have surface active properties comparable to substances used as absorption enhancers of poorly absorbed drugs. The intestinal epithelium serves as a gatekeeping barrier for the absorption of toxic substances, nutrients and drugs. READ MORE