Search for dissertations about: "phase 3 trials"

Showing result 1 - 5 of 62 swedish dissertations containing the words phase 3 trials.

  2. 1. Patients in Clinical Cancer Trials : Understanding, Motivation and Hope

    Author : Tove Godskesen; Ulrik Kihlbom; Peter Nygren; Karin Nordin; Peter Strang; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; adults; clinical trials; phase 1 trials; phase 3 trials; patient information; patient education; informed consent; hope;

    Abstract : The overall aim of this thesis was to study participants' understanding of clinical cancer trials, and their motivation for participation. Of particular interest was the question of whether the patients hoped for a cure resulting from the trial. READ MORE

  4. 2. Mantle cell lymphoma strategies in primary treatment

    Author : Alexandra Albertsson Lindblad; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mantle cell lymphoma; registry data; Clinical Trial; Phase I; Clinical Trial; Phase II; rituximab; bendamustine; lenalidomid; ibrutinib; ADCC; in vitro model; TP53 mutations; watchful waiting; mantle cell lymphoma; real-world data; lenalidomide; rituximab; bendamustin; ibrutinib; ADCC; TP53 mutation; CDKN2A; NGS; MIPI; Watchful waiting;

    Abstract : Mantle cell lymphoma (MCL) is associated with poor prognosis due to an aggressive clinical course. Being a rare disease, there are few randomized trials in MCL and there is no defined golden standard in primary treatment. READ MORE

  5. 3. Effect of quinoline-3-carboxamides on myeloid cells in inflammation and cancer

    Author : Adnan Deronic; Immunologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Quinoline-3-carboxamide; myeloid cell; inflammation; cancer; peritonitis; mammary carcinoma; fibrosis;

    Abstract : The quinoline-3-carboxamides (Q compounds) are a family of small molecules that ameliorate various types of murine inflammatory autoimmune disease. One such compound has also demonstrated anti-tumor effects in murine tumor models. READ MORE

  6. 4. Upholding the coral loop : Resilience, alternative stable states and feedbacks in coral reefs

    Author : Albert Norström; Magnus Nyström; Nancy Knowlton; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; resilience; alternative stable states; regimes; feedbacks; recruitment; coral reefs; marine ecosystem management; regime shifts; phase shifts; Marine ecology; Marin ekologi; naturresurshushållning; Natural Resources Management;

    Abstract : Coral reefs are suffering unprecedented declines in coral cover and species diversity. These changes are often associated with  substantial shifts in community structure to new dominant organisms. Ultimately, these “phase shifts” can be persistent and very difficult to return from. READ MORE

  7. 5. Targeting the role of statins in breast cancer – through translationally edged clinical trials

    Author : Maria Feldt; Bröstcancer - prevention & intervention; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : AbstractBreast cancer incidence is increasing, and despite major progress in the treatment, breast cancer is still the leading cause of death from cancer among women. Thus, there is a constant need for new treatment options. READ MORE