Search for dissertations about: "phd dissertations for medical laboratory sciences"
Showing result 1 - 5 of 24 swedish dissertations containing the words phd dissertations for medical laboratory sciences.
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1. Ligand-based Methods for Data Management and Modelling
Abstract : Drug discovery is a complicated and expensive process in the billion dollar range. One way of making the drug development process more efficient is better information handling, modelling and visualisation. The majority of todays drugs are small molecules, which interact with drug targets to cause an effect. READ MORE
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2. Tamiflu in the Water : Resistance Dynamics of Influenza A Virus in Mallards Exposed to Oseltamivir
Abstract : The natural reservoir of influenza A virus (IAV) is wild waterfowl, and all human IAVs have their genetic origins from avian viruses. Neuraminidase inhibitors (NAIs) are currently the best drugs for treatment of human influenza; therefore, the orally available NAI oseltamivir (Tamiflu®) has been stockpiled worldwide as part of pandemic preparedness planning. READ MORE
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3. Extracellular Matrix Based Materials for Tissue Engineering
Abstract : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. READ MORE
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4. Early rheumatoid arthritis : biomarkers and hormonal factors in relation to disease progression
Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, affecting approximately 0.5 to 1% of the adult population. Although the aetiology is not fully known, a complex interaction between genetic, environmental and stochastic factors is thought to trigger the pathogenic mechanisms. READ MORE
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5. Targeting molecular mechanisms for epigenetic silencing in multiple myeloma : Implications for biology and precision medicine
Abstract : Multiple myeloma (MM) is a heterogeneous haematological cancer where malignant plasma cells clonally expand within the bone marrow. The transcriptional repressor PRC2 and its catalytic subunit EZH2 play a major role in MM, as PRC2 re-targeting results in a MM-specific gene silencing profile. READ MORE