Search for dissertations about: "pheochromocytoma"

Showing result 11 - 15 of 26 swedish dissertations containing the word pheochromocytoma.

  2. 11. Exploring inter- and intra-heterogeneity in childhood neuroblastoma and pheochromocytoma

    Author : Wenyu Li; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neuroblastoma is the most common extra-cranial solid tumor of the sympathoadrenal cell lineage, which is a unique pediatric malignancy with remarkable inter- and intra-tumoral heterogeneity. In infants, neuroblastoma can regress spontaneously without treatment, while in older patients, neuroblastoma can develop with lethal progression with less than a 50% survival rate. READ MORE

  4. 12. Further delineation of molecular alterations in adreno-medullary tumors

    Author : Janos Geli; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Pheochromocytoma; abdominal paraganglioma; neuroblastoma; tumor suppressor gene; DNA methylation; gene expression; RIZ1; NORE1A; RASSF1A; CDKN2A;

    Abstract : Pheochromocytomas, abdominal paragangliomas and neuroblastomas are tumors of the sympathetic nervous system. Anatomically pheochromocytomas and abdominal paragangliomas arise from sympathoadrenal paraganglia, within and outside the adrenal medulla, respectively. READ MORE

  5. 13. Endocrine tumour development : with special focus on chromosome arms 1p and 11q

    Author : Brita Nord; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Endocrine tumour; Follicular thyroid tumour; Malignant melanoma; Midgut carcinoid; Pheochromocytoma; Abdominal paraganglioma; Merkel cell carcinoma; MEN1; SDHD; RIZ;

    Abstract : The overall goal of this thesis has been to characterise the involvement of chromosome arms 1p and 11 q in the development of endocrine tumours. The MEN1 gene was analysed as a candidate tumour suppressor gene by screening for mutations in follicular thyroid tumours, malignant melanomas, pheochromocytomas, and abdominal paragangliomas. READ MORE

  6. 14. DNA methylation and gene expression patterns in adrenal medullary tumors

    Author : Nimrod G B Kiss; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pheochromocytomas and abdominal paragangliomas are neuroendocrine tumors of the autonomous nervous system, arising in adrenal medulla and sympathetic ganglia throughout the abdomen. These tumors originate from catecholamine-producing chromaffin cells. Neuroblastomas are common childhood tumors in the adrenal medulla and abdominal ganglia. READ MORE

  7. 15. The Tyrosine Kinase GTK : Signal Transduction and Biological Function

    Author : Cecilia Annerén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinases; GTK; SHB; proliferation; survival; differentiation; β cells; pancreatectomy; cytokines; diabetes; PC12 cells; NGF; streptozotocin; focal adhesion kinase; RAP1; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. READ MORE