Search for dissertations about: "pheomelanin"

Showing result 1 - 5 of 8 swedish dissertations containing the word pheomelanin.

  1. 1. Pheomelanin markers in melanoma with reference to their excretion into urine

    Author : Dzeneta Nezirevic Dernroth; Bertil Kågedal; Christer Hansson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pheomelanin; melanoma; benzothiazole; aminohydroxyphenylalanine; diffuse melanosis; HILIC; Clinical chemistry; Klinisk kemi;

    Abstract : Skin pigmentation is an important issue in most cultures. Until recently we have not understood the most important elements of pigmentation regarding detailed chemical structure. READ MORE

  2. 2. Dissecting Phenotypic Variation in Pigmentation using Forward and Reverse Genetics

    Author : Anders R Hellström; Uppsala universitet; []
    Keywords : Pigmentation; eumelanin; pheomelanin; knockout; Silver; SLC45A2; PMEL17; Sex-linked barring; CDKN2A; CDKN2B; ARF; chicken; Japanese quail; MEDICINE; MEDICIN; Molekylär genetik; Molecular Genetics;

    Abstract : Coat color and patterning phenotypes have been extensively studied as a model for advancing our understanding of the relationship between genetic and phenotypic variation. In this thesis, genes of relevance for pigment cell biology were investigated. The dissertation is divided in two parts. READ MORE

  3. 3. Melanogenesis as the basis for melanoma targeting

    Author : Ulla Mårs; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

    Abstract : The incidence of malignant melanoma has increased rapidly during the last decades, and the prognosis for disseminated melanoma is poor. The melanoma cells produce melanin, and therefore the melanogenesis may serve as a target for treatment of melanotic melanoma; thioureyelenes such as thiourea and 2-thiouracil, e.g. READ MORE

  4. 4. Genetic Studies of Pigmentation in Chicken

    Author : Ulrika Gunnarsson; Leif Andersson; Göran Andersson; Susanne Kerje; William J. Pavan; Uppsala universitet; []
    Keywords : ;

    Abstract : Domestic animals have been selected by humans for thousands of years, which have drastically altered their genetic constitution and phenotypes. In this thesis, several of the most important genes causing pigmentation differences between the wild red junglefowl (Gallus gallus) and domestic chickens have been identified. READ MORE

  5. 5. Photochemistry of Eumelanin Precursors Role of Excited State Proton Transfer for UV Photoprotection

    Author : Alice Corani; Kemisk fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Time-resolved; Fluorescence spectroscopy; Excited State Proton Transfer ESPT ; Photochemistry; Eumelanin; Melanin;

    Abstract : Melanin is an epidermal pigment commonly known to give darker skin coloration under sun exposure. It is also present in the hair, eyes, inner ear and brain. READ MORE