Search for dissertations about: "phosphocreatine"

Showing result 1 - 5 of 15 swedish dissertations containing the word phosphocreatine.

  2. 1. The role of exercise and exercise-related factors in the control of mitochondrial oxidative function

    Author : Brandon Walsh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Skinned fibers; permeabilized fibers; skeletal muscle; exercise; mitochondria; ADP sensitivity; aerobic metabolism; training; eccentric; high intensity; creatine; phosphocreatine; inorganic phosphate; hydrogen ions;

    Abstract : The effects of exercise and exercise-related factors on the control of mitochondrial oxidative function were investigated in human and rat skeletal muscle. Oxidative function was assessed through the measurement of oxygen consumption in chemically permeabilized (skinned) fibers. READ MORE

  4. 2. Studies of diaphragm fatigue and dysfunction

    Author : Peter J Radell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Diaphragm function; contractility; fatigue; oxidative metabolism; 31phosphorus nuclear magnetic spectroscopy; ultrasonography; prolonged ventilation; compound muscle action potential; myopathy; electroneurography; muscle fiber; morphology.;

    Abstract : Diaphragm fatigue and dysfunction are important components of acute and chronic respiratory pump failure. We lack knowledge about the nature of diaphragm fatigue and the pathophysiological and morphological changes that occur in the diaphragm after prolonged mechanical ventilation. This thesis studied two aspects of diaphragm function. READ MORE

  5. 3. Significance of mitochondrial ultrastructure for bioenergetics

    Author : Alexandra Toth; Martin Ott; Vladimir Gogvadze; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioenergetics; mitochondrial ultrastructure; respiratory chain; Saccharomyces cereviciae; ATP synthase; apoptosis; cytochrome c; supercomplexes; Biochemistry; biokemi;

    Abstract : Mitochondria are the site where most of the energy from food is converted into adenosine triphosphate (ATP). This process is taking place at the inner membrane (IM) of mitochondria, and is called oxidative phosphorylation, and results in the establishment of a proton motive force (pmf). READ MORE

  6. 4. Energy-Related Metabolites during and after Induced Myocardial Ischemia and Retroperfusion of the Coronary Sinus : An Experimental Study in the Pig with the Microdialysis Technique and Extracorporeal Circulation

    Author : Vitas Zemgulis; Rolf Ekroth; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Ischemia; myocardial infarction; reperfusion; energy metabolism; coronary sinus retroperfusion; microdialysis; taurine; nucleoside transport; adenosine; aerobic lactate production; Kirurgi; Surgery; Kirurgi; Thoracic and Cardivascular Suregery; kirurgi; särskilt thoraxkirurgi;

    Abstract : In the clinical setting great efforts have been made with contradictory results to operate upon acutely myocardial ischemic patients. The reasons for the absence of unambiguous results are not well understood nor are they scientifically explored. READ MORE

  7. 5. Changes in mitogen-activated protein kinase phosphorylation and inorganic phosphate induced by skeletal muscle contraction

    Author : Charlott Wretman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Skeletal muscle; MAP kinase; signal transduction; contraction; acute exercise; exercise intensity; fibre-type; concentric; ROS; eccentric.;

    Abstract : Skeletal muscles adjust to the level of contractile activity by different biochemical alterations. Contraction is a multifactorial stimulus with short-term metabolic effects and long-term responses due to changes in protein synthesis. READ MORE