Search for dissertations about: "phylogenetic footprinting"

Found 2 swedish dissertations containing the words phylogenetic footprinting.

  2. 1. Computational and experimental approaches to regulatory genetic variation

    Author : Malin Andersen; Jacob Odeberg; John Peden; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Molecular biology; Genetics; single nucleotide polymprhism SNP ; regulatory SNP; transcription factor binding site; phylogenetic footprinting; allelic imbalance; EMSA; CD36; cardiovascular disease.; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : Genetic variation is a strong risk factor for many human diseases, including diabetes, cancer, cardiovascular disease, depression, autoimmunity and asthma. Most of the disease genes identified so far alter the amino acid sequences of encoded proteins. READ MORE

  4. 2. In silico prediction of CIS-regulatory elements

    Author : Albin Sandelin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Transcriptional regulation; transcription factor binding sites; phylogenetic footprinting; pattern finding; pattern comparison;

    Abstract : As one of the most fundamental processes for all life forms, transcriptional regulation remains an intriguing and challenging subject for biomedical research. Experimental efforts towards understanding the regulation of genes is laborious and expensive, but can be substantially accelerated with the use of computational predictions. READ MORE