Search for dissertations about: "physics of blood flow"

Showing result 1 - 5 of 18 swedish dissertations containing the words physics of blood flow.

  1. 1. Cerebral blood flow and intracranial pulsatility studied with MRI : measurement, physiological and pathophysiological aspects

    Author : Anders Wåhlin; Anders Eklund; Jan Malm; Richard Birgander; William G Bradley; Umeå universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Arterial Pulsatility; cerebrospinal fluid; cerebral blood flow; venous flow; intracranial pressure; pulse pressure; dementia; hippocampus; multiple sclerosis; magnetic resonance imaging; radiofysik; radiation physics;

    Abstract : During each cardiac cycle pulsatile arterial blood inflates the vascular bed of the brain, forcing cerebrospinal fluid (CSF) and venous blood out of the cranium. Excessive arterial pulsatility may be part of a harmful mechanism causing cognitive decline among elderly. READ MORE

  2. 2. Advances in quantitative emission tomography : development and analysis of methods for validation and correction

    Author : Cathrine Jonsson; Magnus Dahlbom; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SPECT; Quantification; rCBF; Scatter correction; Phantoms; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : The nuclear medicine imaging techniques SPECT and PET are sensitive tools in mapping various physiological and biochemical processes in vivo. This work was devoted to investigations of methodological and physical properties of the SPECT technique as well as developing methods for validation and correction. READ MORE

  3. 3. Nuclear magnetic resonance and microcirculation: The influence of pulsatile brain-tissue motion on measurements of intravoxel incoherent motion and assessment of haemodynamics using exo- and endogenous tracers

    Author : Ronnie Wirestam; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diagnostic radiology; cortical activation; diffusion; tumor; tumour; ischemic stroke; ischaemic stroke; tracer kinetics; bolus tracking; phase mapping; brain motion; intracranial dynamics; blood flow; haemodynamics; vascularity; MRS; perfusion; MRI; magnetic resonance; Clinical physics; radiology; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Abstract : In this project, the potential of magnetic resonance (MR) imaging and spectroscopy in studies of microcirculation and haemodynamics was evaluated. The spatial and temporal characteristics of human pulsatile brain-tissue movements in healthy individuals, relevant for the understanding of the cerebrospinal-fluid (CSF) circulation and the pathogenesis of hydrocephalus, were thoroughly investigated. READ MORE

  4. 4. Microfluidics Separation and Analysis of Biological Particles

    Author : Jason Beech; Fasta tillståndets fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Point-of-care; Lab-on-a-chip; Microfluidics; Separation science; Deterministic Lateral Displacement; morphology; deformability; Fysicumarkivet A:2011:Beech;

    Abstract : In the last decade, powerful communication and information technology in the form of the mobile phone has been put into the hands of more than 50% of the global population. In stark contrast, a lack of access to medical diagnostic technology with which to diagnose both communicable and non-communicable diseases will mean that many of these people will die of easily treatable conditions. READ MORE

  5. 5. Optimisation and Validation of Dynamic Susceptibility Contrast MRI Perfusion Measurements

    Author : Linda Knutsson; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nukleärmedicin; radiobiologi; Nuclear medicine; radiobiology; radiologi; tomografi; medicinsk instrumentering; tomography; medical instrumentation; Clinical physics; cerebral blood volume; mean transit time; cerebral blood flow; perfusion; dynamic susceptibility contrast MRI arterial input function; Klinisk fysiologi; radiology;

    Abstract : The studies presented in this thesis concern the optimisation and evaluation of the dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) technique for the assessment of perfusion-related parameters of the brain, such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT). Several methodological factors influence these measurements, for example, contrast-agent administration, arterial input function (AIF) registration, choice of deconvolution algorithm and the choice of pulse-sequence parameters. READ MORE