Search for dissertations about: "physiological characteristics"

Showing result 6 - 10 of 180 swedish dissertations containing the words physiological characteristics.

  2. 6. Zopiclone degradation in biological samples : Characteristics and consequences in forensic toxicology

    Author : Gunnel Nilsson; Robert Kronstrand; Fredrik C. Kugelberg; Johan Ahlner; Mikael Hedeland; Linköpings universitet; []
    Keywords : ;

    Abstract : Bio-analytical results are influenced by in vivo factors such as genetics, pharmacological and physiological conditions and in vitro factors such as specimen composition, sample additives and storage conditions. Zopiclone (ZOP) is a short-acting hypnotic drug (Imovane®) used for treatment of insomnia. READ MORE

  4. 7. In vitro wound healing characteristics of amelogenins

    Author : Sofia Almqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amelogenins; extracellular matrix; cell culture; macrophage; fibroblast; endothelial cell; integrin; cytokine; inflammation; wound healing tissue repair;

    Abstract : Wound healing involves the co-ordinated actions of several cell types, soluble cell mediators and extracellular matrix (ECM). This research project intended to investigate the role of certain ECM proteins in different processes during tissue repair by studying the interaction between dermal cells and ECM. READ MORE

  5. 8. Interaction Characteristics of Viral Protease Targets and Inhibitors : Perspectives for drug discovery and development of model systems

    Author : Cynthia F Shuman; Jordan J N Tang; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; viral proteases; biomolecular interactions; kinetics; thermodynamics; biosensors; drug discovery; Biokemi; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : Viral proteases are important targets for anti-viral drugs. Discovery of protease inhibitors as anti-viral drugs is aided by an understanding of the interactions between viral protease and inhibitors. This thesis addresses the characterization of protease-inhibitor interactions for application to drug discovery and model system development. READ MORE

  6. 9. Numerical Simulation of Unsteady Flows of Physiological Relevance

    Author : Philip Evegren; Institutionen för energivetenskaper; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Wall shear stress; Biofluid mechanics; Pulsatile flow; Atherosclerosis; Flow in bifurcations;

    Abstract : Pulsatile flows in geometries of physiological relevance have been investigated. Atherosclerotic plaques are (initiated) near junctions and bifurcations in larger arteries. The flow in these regions is characterized by flow separation and unsteadiness, which indicates that local flow conditions contribute to atherogenesis. READ MORE

  7. 10. Physiological aspects of cochlear excitation and neurotransmitter release

    Author : Wanje Jäger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cochlea; cochlear microphonics; summating potential; vibratory response; tetracaine; aspartate; glutarnate; neurotransmitter; noise; hearing loss;

    Abstract : Using an in vitro model of the guinea pig, the temporal bone preparation, cochlear physiology was studied. By perfusion of the scala tympani with oxygenated culture medium, the responses of the hearing organ to sound stimuli were maintained over several hours and the functional state was followed by monitoring the electrophysiological parameters cochlear microphonics (CM) and summating potential (SP). READ MORE