Search for dissertations about: "piecemeal degranulation"
Found 3 swedish dissertations containing the words piecemeal degranulation.
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1. Assessment of eosinophil degranulation in allergic diseases and experimental models
Abstract : In allergic disorders, the eosinophilic granulocytes migrate to affected tissues and release granule proteins with cytotoxic, immunoregulatory, and remodeling-promoting properties. Given that degranulation is reflected by a loss in eosinophil granule density of living cells, or by cell membrane rupture and release of intact granules, these morphological changes may represent a biomarker of the allergic disease. READ MORE
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2. Mechanisms of granule protein mobiliation in blood eosinophils
Abstract : Serum levels of eosinophil granule proteins namely ECP, EPO and EPX, which are stored in the matrix of specific granules, were shown to correlate with the course of disease in disorders involving eosinophils. The concentration of eosinophil proteins in serum is the result of their release in vivo and ex vivo during the sampling procedure. READ MORE
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3. Symptoms and aspects on eosinophil activity in allergic rhinitis
Abstract : Allergic rhinitis is a major atopic disease. Even if much is known about the pathophysiology of this condition, and despite the fact that good treatments are available, there is a need for new treatment options, particularly for such aiming at new targets and reduced side effects. READ MORE