Search for dissertations about: "pim-1"
Showing result 1 - 5 of 7 swedish dissertations containing the word pim-1.
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1. Molecular Studies of Diamond-Blackfan Anemia and Congenital Nail Dysplasia
Abstract : The aim of this thesis is to investigate the effect of genetic mutations on the pathophysiology of two human disorders: Diamond-Blackfan Anemia (DBA) and isolated congenital nail dysplasia. The first part of this thesis (Paper I-III) investigates the mechanism associated with DBA. READ MORE
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2. Nanoplasmonic Sensing of Materials for Energy Applications
Abstract : Sensors are omnipresent in our daily life. They are used in many applications ranging from the touch screen in our smartphones to more critical contexts such as pollution monitoring. READ MORE
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3. Early oncogenic events and defective apoptosis in prostate cancer
Abstract : Prostate cancer is one of the most common malignancies in males in the Western world. Although the mechanisms are unclear, it is generally believed that the accumulation of genetic alterations leads to the tumor formation. READ MORE
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4. Ribosomal Proteins in Diamond-Blackfan Anemia : Insights into Failure of Ribosome Function
Abstract : Diamond-Blackfan anemia (DBA) is a severe congenital anemia characterized by a defect in red blood cell production. The disease is associated with growth retardation, malformations, a predisposition for malignant disease and heterozygous mutations in either of the ribosomal protein (RP) genes RPS7, RPS17, RPS19, RPS24, RPL5, RPL11 and RPL35a. READ MORE
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5. A study of the transition from premalignancy to clinical prostate cancer
Abstract : Prostate cancer remains the most commonly diagnosed life-threatening malignancy and the second leading cause of death from cancer in men. However, little is known about molecular mechanisms that underline its initiation and progression. READ MORE