Search for dissertations about: "pindolol"

Found 4 swedish dissertations containing the word pindolol.

  1. 1. Stereoselective Transport of Drugs Across the Blood-Brain Barrier (BBB) In Vivo and In Vitro Pharmacokinetic and Pharmacodynamic Studies of the (S)- and (R)-Enantiomers of Different 5-HT1A Receptor Agonists and Antagonists

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hongmei Yan; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; pindolol; propranolol; 2- di-n-propylamino tetralin; racemate; enantiomer; drug distribution; brain; rat; blood-brain barrier; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Psychiatry; psykiatri;

    Abstract : Delivery of drugs to the brain requires passage across the blood-brain barrier (BBB). Both for drugs already on the market and for new drugs under development, it is important to know to what extent a drug enters the CNS. Many drugs used clinically are racemic mixtures, i.e. READ MORE

  2. 2. Positron emission tomography in serotonergic drug development

    University dissertation from Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Author : Bengt Andrée; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; 5-HT1A receptors; 5-HT2A receptors; D2 dopamine receptors; antidepressive drugs; antipsychotic drugs; pindolol; NAD-299; S 16924; ORG 5222; M100907; WAY; DWAY;

    Abstract : The serotonin neurotransmission system has a central role in drug treatment of depression and anxiety and is also discussed in relation to treatment of schizophrenia. The benefits of presently available drugs are however limited by partial of poor response and side effects. READ MORE

  3. 3. Noradrenergic augmentation strategies in the pharmacological treatment of depression and schizophrenia : An experimental study

    University dissertation from Stockholm : Karolinska Institutet, Department of Physiology and Pharmacology

    Author : Love Linnér; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The pharmacological treatment of depression and schizophrenia, two major psychiatric disorders, is largely based on modulation of central monoaminergic neurotransmission. However, currently available pharmacological treatment alternatives possess a relatively modest clinical efficacy, making them less than optimal. READ MORE

  4. 4. Bronchial hyperresponsiveness of ß-adrenoceptor agonists and antagonists in guinea pig airways

    University dissertation from Linköping : Linköpings universitet

    Author : Fredrik Johansson; Linköpings universitet.; Linköpings universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : Asthma is one of the most common diseases in the industrialised countries. The underlying mechanisms are complex and still not fully understood although inflammation of the airways plays an important role. READ MORE