Search for dissertations about: "piperazine"

Showing result 6 - 10 of 11 swedish dissertations containing the word piperazine.

  2. 6. Biological and air monitoring of exposure to isocyanates

    Author : Carl Johan Sennbro; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; industrial medicine; Occupational health; asthma; protein adducts; polyurethane; biomarkers; occupational exposure; DBA; ICA; NDI; MDI; TDI; Diisocyanates; Isocyanates; Biomonitoring; Air monitoring; arbetsmiljömedicin; Yrkesmedicin;

    Abstract : Exposure to isocyanates may induce disorders in the airways of workers. Therefore, application, development and validation of methods for exposure assessment is of great importance. READ MORE

  4. 7. Design, Synthesis and Characterization of Small Molecule Inhibitors and Small Molecule : Peptide Conjugates as Protein Actors

    Author : Jonas Nilsson; Lars Baltzer; Ingemar Kvarnström; Thomas Olsson; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Synthetic receptor; Peptide inhibitor conjugate; Peptide protein surface interactions; General Lead Discovery Library; Combinatorial Chemistry; Solid Phase Chemistry; Targeted Library; Thrombin inhibitor; Fluorescence; Surface Plasmon Resonance; Organic chemistry; Organisk kemi;

    Abstract : This thesis describes different aspects of protein interactions. Initially the function of peptides and their conjugates with small molecule inhibitors on the surface of Human Carbonic Anhydrase isoenzyme II (HCAII) is evaluated. READ MORE

  5. 8. Platelet-activating factor, intestinal epithelial cells, and Chron's disease : An experimental study

    Author : Bengt Kald; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Platelet-activating factor (PAF-acethcr, 1-0-alky l-2-acetyl-s n- glycero-3- phosphocholine), is a potent inflammatory mediator that can be formed by a variety of cells and tissues. In the present investigation, the content of PAFacether was determined in mucosal biopsies from the ileum and colon of patients with Crohn's disease and control patients. READ MORE

  6. 9. Synthesis, Pharmacological Characterization and QSAR Modelling of 4-Phenylpiperidines and 4-Phenylpiperazines Effects on the dopaminergic neurotransmission in vivo

    Author : Fredrik Pettersson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dopamine; D2; monoamine oxidase; DOPAC; in vivo; QSAR; dopaminergic stabilizer;

    Abstract : The endogenous neurotransmitter dopamine (DA) is involved in several functions that are controlled from the central nervous system (CNS), for example behaviour, memory, cognition and reward. A disturbed dopaminergic neurotransmission may lead to many severe conditions, such as schizophrenia, attention deficit hyperactivity disorder (ADHD) or Parkinson's disease (PD). READ MORE

  7. 10. Novel framework materials : organically templated silicogermanates and hybrid fluorotitanates

    Author : Liqiu Tang; Xiaodong Zou; Gunnar Svensson; Gies Hermann; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; framework materials; silicogermanates; hybrid fluorotitananates; Chemistry; Kemi;

    Abstract : Two types of novel framework materials, including six organically templated silicogermanates and five hybrid fluorotitanates, have been synthesized, and their structures have been determined by single crystal X-ray diffraction. Their structures and the interactions between the organic and inorganic species are discussed in some detail. READ MORE