Search for dissertations about: "piperidine"

Showing result 1 - 5 of 14 swedish dissertations containing the word piperidine.

  1. 1. Reaction Between Grignard reagents and Heterocyclic N-oxides Synthesis of Substituted Pyridines, Piperidines and Piperazines

    University dissertation from Umeå : Umeå universitet

    Author : Hans Andersson; Umeå universitet.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Grignard reagents; pyridine N-oxide; pyrazine N-oxide; dienal-oxime; pyridine; ortho- metalation; piperidine; piperazine; asymmetric; NATURAL SCIENCES Chemistry Organic chemistry Organic synthesis; NATURVETENSKAP Kemi Organisk kemi Organisk syntes; organisk kemi; Organic Chemistry;

    Abstract : This thesis describes the development of new synthetic methodologies for preparation of bioactive interesting compounds, e.g. substituted pyridines, piperidines or piparazines. Thesecompounds are synthesized from commercially available, cheap and easily prepared reagents, videlicet the reaction between Grignard reagents and heterocyclic N-oxides. READ MORE

  2. 2. Isolation, Synthesis and Structure-Activity Relationships of Antifeedants against the Pine Weevil, Hylobius Abietis

    University dissertation from Stockholm : KTH

    Author : Carina Eriksson; KTH.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Pine weevil; Hylobius abietis; semiochemicals; antifeedant; feeding deterrent; feeding stimulant; bark extract; carboxylic acid; piperidine alkaloids; structure-activity; cinnamic aldehyde; benzaldehyde; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : The large pine weevil, Hylobius abietis L., is a major insect pest on conifer seedlings in northern Europe. Due to its feeding newly planted trees get girdled, resulting in high seedling mortality (up to 80%). As a consequence great financial losses to the forest industry occur. READ MORE

  3. 3. Development of novel serotonin 5-HT6 and dopamine D2 receptor ligands and MAO A inhibitors - Synthesis, structure-activity relationships and pharmacological characterization

    University dissertation from Stockholm : KTH

    Author : Cecilia Mattsson; Göteborgs universitet.; Gothenburg University.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dopamine D2 receptor; serotonin reuptake transporter; monoamine oxidase; 5-HT6 receptor; DOPAC; 5-HIAA; 3-tetrahydropyridine indole; 3-piperidine indole; 3- pyrrolidin-1-ylmethyl chromen-2-one;

    Abstract : It is known since the 1950s that enhancement of the levels of the monoamines dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) in the brain will relieve the symptoms of major depression, and current therapies are still based on this mechanism. However, all available antidepressants today are still suffering from slow onset of therapeutic action, as well as adverse effects and lack of efficacy. READ MORE

  4. 4. Amphiphilic Molecules in Aqueous Solution

    University dissertation from Stockholm : KTH

    Author : Gerd Persson; Umeå universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; liquid crystal; phase diagrams; counterions; alkylpyridinium octanesulfonates; 1-monooleoyl-rac-glycerol; n-octyl-β-D-glucoside; cubic phases; Fysikalisk kemi; NATURAL SCIENCES Chemistry Physical chemistry; NATURVETENSKAP Kemi Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Abstract : The aim of this thesis was to investigate amphiphilic molecules in aqueous solution. The work was divided into two parts. In the first part the effects of different counterions on phase behavior was investigated, while the second part concerns the 1-monooleoyl-rac-glycerol (MO)/n-octyl-β-D-glucoside (OG)/2H2O-system. READ MORE

  5. 5. C–H activation through late transition metal cyclometallation. Addressing selectivity and reactivity problems

    University dissertation from Department of Chemistry, Lund University

    Author : Mikhail Kondrashov; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; C—H activation; cyclometallation; pincer ligands; anion exchange; bimetallic complexes; oxidative functionalisation;

    Abstract : The ligand-directed C—H activation relies on a coordinating donor atom being in proximity to the C—H bond activated. Cyclometallation of 2-(1-naphthyl)-pyridine – a substrate containing both γ- and δ-positions in proximity to the directing nitrogen atom – was studied. READ MORE