Search for dissertations about: "piperidine"
Showing result 1 - 5 of 15 swedish dissertations containing the word piperidine.
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1. Reaction Between Grignard reagents and Heterocyclic N-oxides : Synthesis of Substituted Pyridines, Piperidines and Piperazines
Abstract : This thesis describes the development of new synthetic methodologies for preparation of bioactive interesting compounds, e.g. substituted pyridines, piperidines or piparazines. Thesecompounds are synthesized from commercially available, cheap and easily prepared reagents, videlicet the reaction between Grignard reagents and heterocyclic N-oxides. READ MORE
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2. Isolation, Synthesis and Structure-Activity Relationships of Antifeedants against the Pine Weevil, Hylobius Abietis
Abstract : The large pine weevil, Hylobius abietis L., is a major insect pest on conifer seedlings in northern Europe. Due to its feeding newly planted trees get girdled, resulting in high seedling mortality (up to 80%). As a consequence great financial losses to the forest industry occur. READ MORE
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3. Development of novel serotonin 5-HT6 and dopamine D2 receptor ligands and MAO A inhibitors - Synthesis, structure-activity relationships and pharmacological characterization
Abstract : It is known since the 1950s that enhancement of the levels of the monoamines dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) in the brain will relieve the symptoms of major depression, and current therapies are still based on this mechanism. However, all available antidepressants today are still suffering from slow onset of therapeutic action, as well as adverse effects and lack of efficacy. READ MORE
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4. Amphiphilic Molecules in Aqueous Solution
Abstract : The aim of this thesis was to investigate amphiphilic molecules in aqueous solution. The work was divided into two parts. In the first part the effects of different counterions on phase behavior was investigated, while the second part concerns the 1-monooleoyl-rac-glycerol (MO)/n-octyl-β-D-glucoside (OG)/2H2O-system. READ MORE
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5. C–H activation through late transition metal cyclometallation. Addressing selectivity and reactivity problems
Abstract : The ligand-directed C—H activation relies on a coordinating donor atom being in proximity to the C—H bond activated. Cyclometallation of 2-(1-naphthyl)-pyridine – a substrate containing both γ- and δ-positions in proximity to the directing nitrogen atom – was studied. READ MORE