Search for dissertations about: "piperidine"

Showing result 6 - 10 of 13 swedish dissertations containing the word piperidine.

  1. 6. Synthetic Transformations via Metal- and Enzyme-Catalyzed Dynamic Kinetic Resolution

    University dissertation from Stockholm : Institutionen för organisk kemi

    Author : Krisztián Bogár; Jan-Erling Bäckvall; Romas Kazlauskas; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ruthenium; racemization; lipase; dynamic kinetic resolution; secondary alcohol; Candida antarctica lipase B; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : This thesis deals with the preparation of a new half-sandwich type ruthenium(II)- catalyst for racemization of optically active secondary alcohols and the development of a highly efficient method in combination with lipases such as Candida antarctica lipase B and Pseudomonas cepacia lipase for dynamic kinetic resolution of various functionalized alcohols under mild reaction conditions.It was shown that the RuCl(CO)2(η5-C5Ph5) complex can racemize optically active aliphatic and aromatic secondary alcohols at room temperature in rather short times. READ MORE

  2. 7. Development of Lewis acid mediated stereoselective synthesis of nitrogen containing heterocycles

    University dissertation from Stockholm : Kemi

    Author : Åsa Sjöholm Timén; [2003]
    Keywords : organic chemistry;

    Abstract : This thesis deals with the development of syntheticmethodologies for the preparation of enantio- anddiastereomerically enriched nitrogen-containingheterocycles.Asymmetric Lewis acid mediated Diels-Alder reactions with2H-azirines as dienophiles have been studied. READ MORE

  3. 8. Quantum Mechanical Calculations of Thermoelectrical Polymers and Organic Molecules

    University dissertation from Stockholm : Kemi

    Author : Amina Mirsakiyeva; Anna Delin; Clas Persson; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Quantum molecular dynamics; Car-Parrinello molecular dynamics; PEDOT; poly 3; 4-ethylenedioxythiophene ; Physics; Fysik;

    Abstract : The subject of the present licentiate thesis is density functional theorybased electronic structure calculations of organic thermoelectric materials and novel organic molecules. We used the Car-Parrinello molecular dynamics method in order to investigate the electronic structure of “green energy” and “greenchemistry” compounds. READ MORE

  4. 9. Studies towards ß-turn mimetics, synthesis of kedarosamine from threonine, and synthesis of glycopeptides from mucins and gp120

    University dissertation from Organic Chemistry, Lund University

    Author : Tatjana Vuljanic; [1998]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Tn antigen; glycopeptides; glycosylation; diastereselective reduction; kedarosamine; kedarcidin chromophore; amino acids; peptide T; ß-turn mimetic; Organisk kemi; gp120; Organic chemistry;

    Abstract : The secondary structure of proteins is crucial for proper function of the protein in biological systems. Peptide T, an octapeptide from the envelope glycoprotein gp120 of the HIV virus, has previously been shown to be responsible for binding to the CD4 receptor on T helper/inducer lymphocytes. READ MORE

  5. 10. Synthesis, Pharmacological Characterization and QSAR Modelling of 4-Phenylpiperidines and 4-Phenylpiperazines Effects on the dopaminergic neurotransmission in vivo

    University dissertation from Organic Chemistry, Lund University

    Author : Fredrik Pettersson; Göteborgs universitet.; Gothenburg University.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dopamine; D2; monoamine oxidase; DOPAC; in vivo; QSAR; dopaminergic stabilizer;

    Abstract : The endogenous neurotransmitter dopamine (DA) is involved in several functions that are controlled from the central nervous system (CNS), for example behaviour, memory, cognition and reward. A disturbed dopaminergic neurotransmission may lead to many severe conditions, such as schizophrenia, attention deficit hyperactivity disorder (ADHD) or Parkinson's disease (PD). READ MORE