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Showing result 1 - 5 of 153 swedish dissertations matching the above criteria.

  2. 1. Proteins of the Inter-α-inhibitor Family : Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components

    Author : Aneta Kaczmarczyk; Erik Fries; Anders Malmström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; bikunin; inter-α-inhibitor; pre-α-inhibitor; intracellular processing; plasma clearance; extracellular matrix; binding; collagen; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. READ MORE

  4. 2. Monitoring of occupational exposure to antineoplastic drugs

    Author : Maria Hedmer; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; industrial medicine; Occupational health; plasma; urine; renal clearance; risk evaluation; biological monitoring; air monitoring; wipe sampling; occupational exposure; ifosfamide; antineoplastic drugs; cyclophosphamide; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : Antineoplastic drugs are commonly used in the medical treatment of cancer and some other diseases. Workplaces e.g. hospital pharmacies and wards where antineoplastic drugs are used are contaminated with these drugs and health care workers are therefore at risk of getting occupationally exposed. READ MORE

  5. 3. Dual roles for hepatic lectin receptors in the clearance of chilled platelets

    Author : Viktoria Rumjantseva; Göteborgs universitet; []
    Keywords : platelet storage; Asialoglycoprotein receptor; GPIbα; αMβ2; transfusion; clearance;

    Abstract : Platelets for transfusion are stored at room temperature because refrigerated platelets are cleared rapidly from circulation. Room temperature storage causes major inconveniences for blood banks and medical risks for recipients. READ MORE

  6. 4. Numerical Simulation of Some Heat Transfer and Fluid Flow Phenomena for Gas Turbine Blades and a Transonic Turbine Stage

    Author : Fadil Mumic; Värmeöverföring; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; fluiddynamik; plasma; Thermal engineering; applied thermodynamics; plasmas; Gaser; fluid dynamics; Gases; transonic; numerical; heat transfer coefficient; shroud surface; squealer blade tip; flat blade tip; leakage flow; Termisk teknik; termodynamik; turbulence modeling;

    Abstract : With the attempts to achieve higher thermal efficiency, turbine blades are exposed to very high temperature gases and may undergo severe thermal stress and fatigue. Thus, in order to develop optimal cooling strategies and reduce the heat transfer it is important to obtain a good understanding of both the complex flow field and the heat transfer characteristics in turbine rotor/stator hot-gas passages. READ MORE

  7. 5. Glomerular filtration rate in adults : a single sample plasma clearance method based on the mean sojurn time

    Author : Margareta Gref; Kjell Karp; Börje Ljungberg; Umeå universitet; []
    Keywords : Clinical Physiology; klinisk fysiologi;

    Abstract : Glomerular filtration rate (GFR) is a key parameter in evaluating kidney function. After a bolus injection of an exogenous GFR marker in plasma an accurate determination of GFR can be made by measuring the marker concentration in plasma during the excretion. READ MORE