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Showing result 1 - 5 of 34 swedish dissertations matching the above criteria.

  1. 1. Regulation of B cell function by plasmacytoid dendritic cells

    Author : Cornelia Gujer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Dendritic cell;

    Abstract : Dendritic cells (DCs) are early sentinels of pathogen exposure and central in the initiation and orchestration of adaptive immune responses. Apart from the prominent role of DCs in the activation of T cells, DCs have been shown to influence humoral B cell mediated responses. READ MORE

  2. 2. NK cell and dendritic cell interactions in innate immune responses

    Author : Catrine M Persson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NK cells; Dendritic cells; crosstalk; recruitment; activation; CD94 NKG2AQa1; Toxoplasma gondii;

    Abstract : Natural killer (NK) cells are cytotoxic cells of the innate immune system. They have been found to be critical in the defense against infections and also against some tumors. Recent studies have shown that NK cells require signals from accessory cells to induce their recruitment and activation at the site of infection or tumor growth. READ MORE

  3. 3. Mechanisms of dendritic cell maturation induced by intracellular bacteria infection

    Author : Miguel A. Tam; Göteborgs universitet; []
    Keywords : Listeria; Salmonella; dendritic cells; maturation; MyD88; IFN-? ?;

    Abstract : Dendritic cells (DCs) are essential for the development of an immune response against pathogens such as Listeria monocytogenes and Salmonella typhimurium. This is mostly because of their unique capacity to stimulate naïve T cells. READ MORE

  4. 4. The Role of Plasmacytoid Dendritic Cells and Natural Killer Cells in Systemic Lupus Erythematosus

    Author : Niklas Hagberg; Lars Rönnblom; Maija-Leena Eloranta; George Tsokos; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; plasmacytoid dendritic cells; natural killer cells; type I interferon; immune complex; SLAM receptors; autoantibodies; CD94 NKG2A; CD94 NKG2C; Medicinsk vetenskap; Medical Science; Immunologi; Immunology;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production, which can eventually lead to immune complex (IC)-mediated organ damage. Due to the stimulation of plasmacytoid dendritic cells (pDC) by nucleic acid-containing ICs (DNA- or RNA-IC), patients with SLE have an ongoing interferon (IFN)-α production. READ MORE

  5. 5. Endocytosis by human dendritic cells

    Author : Linda Andersson; Malmö högskola; []
    Keywords : human dendritic cells; endocytosis;

    Abstract : Dendritic cells (DCs) are specialized antigen-presenting cells with the ability to internalize antigen, and present antigen-derived peptides to T cells. The functions of DCs depend on the subset, as well as their location and activation state. READ MORE