Advanced search

Showing result 1 - 5 of 48 swedish dissertations matching the above criteria.

2. 1. Plasminogen : a novel inflammatory regulator that promotes wound healing

   Author : Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

   Abstract : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. READ MORE

4. 2. Plasminogen : a pleiotropic inflammatory regulator in radiation-induced wound formation and wound repair

   Author : Mahsa Fallah; Tor Ny; Malgorzata Wilczynska; Robert Medcalf; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The plasminogen activator (PA) system plays important roles in many physiological and pathological processes, including inflammation and wound healing. Plasmin, the central component of the PA system, is a broad-spectrum serine protease that is derived from its inactive precursor form, plasminogen. READ MORE

5. 3. Ovarian tumors. Prevalence, malignancy risk and significance of the Plasminogen activation system

   Author : Christer Borgfeldt; Lund Obstetrik och gynekologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproduktion; andrologi; gynekologi; sexuality; Obstetrik; Ovarian neoplasm; andrology; reproduction; epidemiology; ultrasonography; plasminogen activation; prognosis; gynaecology; Obstetrics; sexualitet;

   Abstract : The aims were to assess the prevalence of ovarian tumors in fertile asymptomatic women and to evaluate the risk of ovarian cancer in women with a history of benign ovarian tumors and endometriosis. In order to search for biomarkers in ovarian tumors, the plasminogen activating (PA) system was studied. READ MORE

6. 4. Molecular analysis of Streptococcus pyogenes and its interactions with the human host

   Author : Andreas Berge; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement activation; fibrinogen; IgG; M protein; C5a peptidase; streptococcal cysteine proteinase; streptokinase; t-PA; Streptococcus pyogenes; plasminogen; C1q; insertional sequence.; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Abstract : Streptococcus pyogenes causes infections only in humans, from trivial tonsillitis to life-threatening conditions. One of its most important virulence factors is the M-like protein family conferring resistance to phagocytosis to the bacterium. The M-like proteins are surface exposed rod-like molecules attached to the cell wall. Each strain of S. READ MORE

7. 5. Plasminogen and protein PAM: Interactions between streptococcal surface proteins and the human fibrinolytic system

   Author : Annika Carlsson Wistedt; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; M protein; streptokinase; kringles; plasmin; Streptococcus pyogenes; plasminogen; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Abstract : Pathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. READ MORE