Search for dissertations about: "plasminogen activation"

Showing result 21 - 25 of 48 swedish dissertations containing the words plasminogen activation.

  2. 21. Studies on fibrin gel structure

    Author : Kamaran T Fatah; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Fibrinogen; fibrin gel structure; plasma; thrombin; fibrinolysis; fibrin gel; zinc ion; plasminogen; crosslinking; acetylsalicylic acid; atherosclerosis; coronary heart disease;

    Abstract : Fibrin gel formation is the final result of interaction between multiple plasma proteins; as a result of activation, fibrinogen is converted to fibrin and crosslinking of fibrin occurs by activated factor XIII, which stabilises the formed clot. Fibrin gel networks were studied in purified fibrinogen systems and in plasma samples from patients with cardiovascular complications and healthy individuals, using light-scattering, turbidity, liquid permeation and confocal 3D microscopy techniques. READ MORE

  4. 22. Hyperbaric oxygen. Effects on ischemia-reperfusion

    Author : Johan Tjärnström; Göteborgs universitet; []
    Keywords : fibrinolysis; f-MLP; human; hyperbaric oxygen; neutrophils; normobaric; PAI-1; PMA; rat; t-PA; trauma; uPA;

    Abstract : Treatment with hyperbaric oxygen (HBO2) is controversial when treating other disorders than decompression sickness. However, HBO2 is a treatment modality that has gained recognition in certain ischemia-reperfusion situations. READ MORE

  5. 23. Plasmin : a potent pro-inflammatory factor

    Author : Yongzhi Guo; Tor Ny; Dick Heinegård; Umeå universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; plasmin; inflammation; rheumatoid arthritis; bacterial arthritis; infection; sepsis; cytokine; signal transduction; Pathology; Patologi;

    Abstract : Plasmin, the central molecule of the plasminogen activator system, is a broad-spectrum serine protease. Plasmin is important for the degradation of fibrin and other components of the extracellular matrix (ECM) during a number of physiological and pathological processes. READ MORE

  6. 24. Invasion promoting factors in endometriotic and endometrial tissue

    Author : Christina Bruse; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Endometriosis; endometrium; PF; tPA; uPA; uPAR; PAI-1; PAI-2; IL-1beta; IL-6; TNFalpha.;

    Abstract : Endometriosis is a common gynaecologic disorder, affecting women of fertile age with pelvic pain and infertility, and is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Retrograde shed endometrial fragments are presumed to adhere to pelvic structures and grow invasively, thereby creating endometriotic tissue. READ MORE

  7. 25. TGFβ Signal Transduction in Endothelial Cells

    Author : Gudrun Valdimarsdóttir; Peter ten Dijke; Carl-Henrik Heldin; Christer Betsholtz; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : Transforming growth factor β (TGFβ) is a multifunctional cytokine that is involved in many biological effects, such as proliferation, migration, differentiation and cell survival. TGFβ regulates cellular responses by binding to a heteromeric complex of type I and type II serine/threonine kinase receptors. READ MORE