Search for dissertations about: "plasminogen activator inhibitor"
Showing result 1 - 5 of 90 swedish dissertations containing the words plasminogen activator inhibitor.
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1. Plasminogen : a pleiotropic inflammatory regulator in radiation-induced wound formation and wound repair
Abstract : The plasminogen activator (PA) system plays important roles in many physiological and pathological processes, including inflammation and wound healing. Plasmin, the central component of the PA system, is a broad-spectrum serine protease that is derived from its inactive precursor form, plasminogen. READ MORE
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2. Tissue-type plasminogen activator : molecular interactions with plasminogen activator inhibitor-1 and endothelial cell-surface proteins
Abstract : .... READ MORE
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3. Plasminogen activator inhibitor type-1 : structure-function studies and its use as a reference for intramolecular distance measurements
Abstract : Inhibitors belonging to the serpin (serine protease inhibitor) family control proteases involved in various physiological processes. All serpins have a common tertiary structure based on the dominant b-sheet A, but they have different inhibitory specificity. READ MORE
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4. Plasminogen activator inhibitor type 2 : a unique serpin with two mobile loops
Abstract : The superfamily of serine protease inhibitors (serpins) is a large group of proteins with diverse functions but a common tertiary structure. Active serpins are highly metastable molecules. Metastability is the property underlying the success and ubiquitousness of serpins. READ MORE
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5. Regional fluxes of tissue plasminogen activator in porcine endotoxemia
Abstract : Formation of fibrin clots in the microcirculation during severe sepsis contributes to organ failure, frequently involving the lungs and the splanchnic organs. Tissue type plasminogen activator, tPA, is the key activator of intravascular fibrinolysis with plasminogen activator inhibitor type-1, PAI-1, as its main inhibitor. READ MORE