Search for dissertations about: "plasminogen"
Showing result 6 - 10 of 152 swedish dissertations containing the word plasminogen.
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6. Regional fluxes of tissue plasminogen activator in porcine endotoxemia
Abstract : Formation of fibrin clots in the microcirculation during severe sepsis contributes to organ failure, frequently involving the lungs and the splanchnic organs. Tissue type plasminogen activator, tPA, is the key activator of intravascular fibrinolysis with plasminogen activator inhibitor type-1, PAI-1, as its main inhibitor. READ MORE
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7. Tissue tropism among group A streptococci - importance of bacteria associated proteolytic activity
Abstract : Group A streptococcus (GAS) is one of the most common of bacterial pathogens infecting humans, frequently causing throat and skin infection. Some GAS strains have surface-expressed virulence factors called M proteins that bind human plasminogen with high affinity. READ MORE
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8. Streptococcus pyogenes and its interactions with the human host
Abstract : We have found that a set of group A streptococcal strains, primarily associated with skin infections, express surface-associated M proteins that bind plasminogen and plasmin with high affinity. The binding is mediated by a common 13 amino acid internal repeated sequence located in the NH2-terminal surface-exposed portion of these M proteins. READ MORE
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9. Molecular analysis of Streptococcus pyogenes and its interactions with the human host
Abstract : Streptococcus pyogenes causes infections only in humans, from trivial tonsillitis to life-threatening conditions. One of its most important virulence factors is the M-like protein family conferring resistance to phagocytosis to the bacterium. The M-like proteins are surface exposed rod-like molecules attached to the cell wall. Each strain of S. READ MORE
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10. Plasminogen activator inhibitor type-1 : structure-function studies and its use as a reference for intramolecular distance measurements
Abstract : Inhibitors belonging to the serpin (serine protease inhibitor) family control proteases involved in various physiological processes. All serpins have a common tertiary structure based on the dominant b-sheet A, but they have different inhibitory specificity. READ MORE