Search for dissertations about: "platelet activation"

Showing result 1 - 5 of 199 swedish dissertations containing the words platelet activation.

  2. 1. Platelet activation and aggregation: Clinical and experimental studies

    Author : Sukhi Singh; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Platelet concentrate; Adrenaline; Noradrenaline; Ticagrelor; Platelet aggregation; Platelet activation;

    Abstract : Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim of this thesis was to identify and evaluate current and potential methods to reduce and prevent bleeding complications in patients with ongoing antiplatelet therapy. READ MORE

  4. 2. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Author : Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Abstract : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. READ MORE

  5. 3. Platelet reactions in the non-self recognition of material surfaces

    Author : Marita Broberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet; biomaterial; adhesion; granule; P-selectin; plasma protein; blood; activation; release;

    Abstract : Every material introduced into the body in order to function in contact with a living tissue is defined as a biomaterial. Biomaterials are used throughout the world in an increasing rate to replace and augment organ functions. The insertion of an implant into the human body will initiate blood coagulation at the surface of the material. READ MORE

  6. 4. Platelet Activation and Inhibition in Connection with Vascular Stents

    Author : Kjeld Christensen; Rolf Larsson; Sten Husted; Uppsala universitet; []
    Keywords : Medicine; platelets; inhibition; activation; stents; ACS; Medicin;

    Abstract : This thesis describes the Chandler loop, which makes it possible to conduct studies in vitro of molecular and cellular interactions between whole blood and stents. It was possible to monitor activation and inhibition of the cascades systems, leukocytes and platelets by combining different platelet inhibitors and heparin coating of stents. READ MORE

  7. 5. Platelet activation and cytokine release during experimental extracorporeal circulation

    Author : Katrin Adrian; Göteborgs universitet; []
    Keywords : ECMO; blood-biomaterial interaction; platelets; platelet activation; cytokines; systemic inflammatory response;

    Abstract : .... READ MORE