Search for dissertations about: "platelet inhibition"

Showing result 1 - 5 of 109 swedish dissertations containing the words platelet inhibition.

  1. 1. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Author : Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Abstract : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. READ MORE

  2. 2. Platelet Inhibition and Bleeding in Coronary Artery Bypass Surgery

    Author : Ulrica Alström; Elisabeth Ståhle; Ulf Schött; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bleeding; cardiac surgery; platelet inhibition; re-exploration; cost analysis; Anaesthetics and intensive care; Anestesiologi och intensivvård; Thoraxkirurgi; Thorax Surgery; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård;

    Abstract : A substantial number of patients undergoing cardiac surgery are on dual anti-platelet treatment with clopidogrel and aspirin. A disadvantage with this treatment is increased risk of bleeding. Bleeding is a complication of major concern associated with adverse outcome for the patient and increased hospital resource utilization. READ MORE

  3. 3. Platelet Activation and Inhibition in Connection with Vascular Stents

    Author : Kjeld Christensen; Rolf Larsson; Sten Husted; Uppsala universitet; []
    Keywords : Medicine; platelets; inhibition; activation; stents; ACS; Medicin;

    Abstract : This thesis describes the Chandler loop, which makes it possible to conduct studies in vitro of molecular and cellular interactions between whole blood and stents. It was possible to monitor activation and inhibition of the cascades systems, leukocytes and platelets by combining different platelet inhibitors and heparin coating of stents. READ MORE

  4. 4. Platelet dysfunction in diabetes : Impact of hyperglycemia and GPIIb/IIIa inhibition

    Author : Masoud Razmara; Karolinska institutet; []
    Keywords : ;

    Abstract : .... READ MORE

  5. 5. Platelet Inhibition in Coronary Artery Disease – Mechanisms and Clinical Importance : Studies with Focus on P2Y12 Inhibition

    Author : Christoph Varenhorst; Stefan James; Agneta Siegbahn; Lars Wallentin; Steen Dalby Kristensen; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndromes; stent thrombosis; P2Y12 inhibitors; thienopyridines; clopidogrel poor response; clopidogrel; prasugrel; Cardiology; Kardiologi; Kardiologi; Cardiology;

    Abstract : Despite the currently recommended dual antiplatelet treatment (DAT) with aspirin and P2Y12 inhibition in patients with coronary artery disease (CAD) there is a risk of adverse clinical outcome. Pharmacodynamic (PD) poor response to clopidogrel occurs in ~ 30% of clopidogrel-treated patients and is associated with an increased risk of recurrent thrombotic events. READ MORE