Search for dissertations about: "platelet inhibition"

Showing result 6 - 10 of 111 swedish dissertations containing the words platelet inhibition.

  2. 6. Platelet Inhibition and Bleeding Complications in Cardiac Surgery Patients - Clinical and experimental studies

    Author : Emma C. Hansson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute coronary syndrome; Bleeding complications; Cardiac surgery; Platelet aggregation inhibitors; Platelet transfusion;

    Abstract : BACKGROUND AND OBJECTIVE Dual antiplatelet therapy (DAPT) with acetylsalicylic acid and a P2Y12 inhibitor (clopidogrel, ticagrelor, or prasugrel) reduces thrombotic events in patients with acute coronary syndrome (ACS), but it is also associated with an increased risk of bleeding complications. The aim of this project was to investigate the prevalence and effects of platelet inhibition in the context of cardiac surgery, the bleeding problems that may occur, and treatment of bleeding complications. READ MORE

  4. 7. Rac1 signaling regulates platelet-dependent inflammation abdominal sepsis

    Author : Rundk Hwaiz; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; Rac1; platelet; neutrophil; chemokine; inflammation;

    Abstract : Sepsis is a systemic inflammatory response syndrome to a localized or systemic infection that leads to the over production of proinflammatory cytokines and the ultimate failure of multiple organ systems. However, little is known about the potential role of Rac1 in controlling sepsis-induced intracellular signaling pathways. READ MORE

  5. 8. Recurrent unexplained first-trimester miscarriage. Effects of acetylcalicylic acid, platelet aggregation and thyroid disease

    Author : Lennart Blomqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acetylsalicylic acid; recurrent miscarriage; platelet aggregation; pregnancy; early pregnancy; first-trimester; live birth; impedance aggregometry; thyroid stimulating hormone; levothyroxine; thyroid peroxidase antibody; arachidonic acid-induced platelet aggregation; platelet activators;

    Abstract : Recurrent unexplained first-trimester miscarriage. Effects of acetylsalicylic acid, platelet aggregation and thyroid disease. Lennart Blomqvist, Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden, 2019. READ MORE

  6. 9. Platelet-dependent pulmonary recruitment of neutrophils in abdominal sepsis

    Author : Milladur Rahman; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; neutrophil recruitment; platelet; lung injury;

    Abstract : Sepsis and subsequent multiple organ failure remain the major cause of mortality in intensive care units. Leukocyte-mediated tissue damage is a key feature in septic lung injury. Accumulating data suggest that platelets play a role in inflammation and tissue injury. READ MORE

  7. 10. Monitoring of coagulation and platelet function in paediatric cardiac surgery

    Author : Birgitta S Romlin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; paediatric cardiac surgery; haemostasis; platelet; coagulation; thromboelastometry; impedance aggregometry; coagulopathy; haemoconcentration;

    Abstract : Abstract Background: Paediatric cardiac surgery has developed dramatically during the last decades. Today, a wide range of patients is operated on-from premature neonates to grown up children with congenital heart disease. Excessive bleeding during and after cardiac surgery is still common, and it is one of the most serious complications. READ MORE