Search for dissertations about: "platelet mRNA"

Showing result 21 - 25 of 36 swedish dissertations containing the words platelet mRNA.

  2. 21. Mechanisms of modulation of PDGFRβ signaling

    Author : Niki Sarri; Carl-Henrik Heldin; Bengt Hallberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF signalling; phosphatase; MKP2; DUSP4; deubiquitinase; USP4; USP17; E3 ligase; Cbl; TRIM21; endoribonuclease; G3BP1; Medicinsk biokemi; Medical Biochemistry; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Platelet-derived growth factors (PDGF) constitute a family of five functional dimers that bind to two structurally related tyrosine kinase receptors i.e. PDGF receptor α and β (PDGFRα and PDGFRβ, respectively), controlling cell growth, proliferation, and migration in cells of mesenchymal origin. READ MORE

  4. 22. Aspects of Chemotherapy in Prostate Cancer

    Author : Åsa Jellvert; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; CRPC; chemotherapy; metronomic; prognostic; predictive; biomarkers;

    Abstract : Since 2004 chemotherapy has been a part of standard of care in prostate cancer (PC) and improved symptom control and survival has been demonstrated in metastatic castration-resistant PC. Whether docetaxel has benefits in earlier stages of PC is currently under investigation. READ MORE

  5. 23. Corneal stromal cell responses to traumatic wounds and topical treatments

    Author : Marina Kulikovska; Per Fagerholm; Neil Lagali; Anders Behndig; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Background. The cornea has unique anatomic, cellular, molecular, and functional features that lead to important mechanistic differences in the process of repair in comparison with what occurs in skin and other organs. The first observable stromal response in corneal wound healing is keratocyte apoptosis. READ MORE

  6. 24. Leukocytes and Coronary Artery Disease : Experimental and Clinical Studies

    Author : Eva Lindmark; Peter Kierulf; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Tissue factor; monocytes; platelets; cytokines; endothelial cells; unstable coronary artery disease; coagulation; inflammation; biochemical markers; IL-6; risk stratification; Biokemi; Biochemistry; Biokemi; Clinical Chemistry; klinisk kemi;

    Abstract : Tissue factor (TF) is the initiator of the coagulation cascade. Monocytes do not normally express TF, but can be induced to do so by certain stimuli. Aberrant TF expression is important in the thrombotic complications of bacterial sepsis, certain malignancies and coronary artery disease (CAD). READ MORE

  7. 25. Growth regulation in sarcomas : studies in vivo and in cell culture

    Author : Avni Abdiu; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Sarcomas are malignant tumors of mesenchymal origin, and can arise in soft-tissue and in bones. It has been suggested that the abnormal growth regulation in sarcoma cells may be due to an autocrine mechanism, in which the cells are stimulated by an endogenous production of growth factors. READ MORE