Search for dissertations about: "platelet mRNA"

Showing result 6 - 10 of 36 swedish dissertations containing the words platelet mRNA.

  2. 6. Experimental and Clinical Studies on Platelet Receptors in Cardiovascular Disease

    Author : Oscar Braun; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; inflammation; athersosclerosis; platelets; thrombosis; Cardiovascular system; Kardiovaskulära systemet;

    Abstract : The crucial role of platelets in maintaining primary hemostais has been evident for a long time and there is now also mounting evidence for their involvement in inflammation. In combination with aspirin, inhibition of the platelet P2Y12 ADP receptor with clopidogrel has become a cornerstone in the antiplatelet in acute coronary syndromes. READ MORE

  4. 7. Platelet angiogenic activities and their regulation on endothelial progenitor cell functions

    Author : Zhangsen Huang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Platelets are essential for haemostasis and thrombosis, but also play a major role in angiogenesis. Activated platelets recruit progenitor cells and induce differentiation into endothelial progenitor cells (EPCs), which contribute importantly to vascular regeneration and endothelium reparation. READ MORE

  5. 8. Transcriptional Regulation of the Platelet-Derived Growth Factor B-receptor by p53 Family Members

    Author : Daniel Wetterskog; Göteborgs universitet; []
    Keywords : ;

    Abstract : Aims: The platelet-derived growth factor ?-receptor (PDGFRB) is critically involved in embryonic development and has a role in many diseases. In cells, signaling through PDGFRB affects growth, migration and death. READ MORE

  6. 9. On vascular endothelial growth factor B and platelet-derived growth factor C : two members of the VEGF/PDGF family of growth factors

    Author : Karin Aase; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Vascular endothelial growth factors (VEGFs), platelet-derived growth factors (PDGFs) and their receptors are important for normal development. They have also been implicated in many pathological conditions. VEGFs have been shown to play an important role in the development of both blood and lymphatic vessels. READ MORE

  7. 10. Developmental origin and molecular regulation of vascular smooth muscle cells

    Author : Per Wasteson; Göteborgs universitet; []
    Keywords : smooth muscle cell; aorta; cell origin; lateral plate mesoderm; paraxial mesoderm; lipoma preferred partner; serum response factor; neointimal hyperplasia; angiotensin II; platelet-derived growth factor-B;

    Abstract : Several pathologies of the vascular system have been suggested to be dependent on the smooth muscle cells (SMCs) that build up the vessel wall. Aortic SMCs have been proposed to derive from lateral plate mesoderm. READ MORE