Search for dissertations about: "platelet recruitment"
Showing result 1 - 5 of 38 swedish dissertations containing the words platelet recruitment.
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1. Platelet-dependent pulmonary recruitment of neutrophils in abdominal sepsis
Abstract : Sepsis and subsequent multiple organ failure remain the major cause of mortality in intensive care units. Leukocyte-mediated tissue damage is a key feature in septic lung injury. Accumulating data suggest that platelets play a role in inflammation and tissue injury. READ MORE
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2. Rac1 signaling regulates platelet-dependent inflammation abdominal sepsis
Abstract : Sepsis is a systemic inflammatory response syndrome to a localized or systemic infection that leads to the over production of proinflammatory cytokines and the ultimate failure of multiple organ systems. However, little is known about the potential role of Rac1 in controlling sepsis-induced intracellular signaling pathways. READ MORE
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3. Microcirculation, Mucus and Microbiota in Inflammatory Bowel Disease
Abstract : Inflammatory bowel diseases, (IBD), are a group of chronic disorders of the gastro-intestinal tract, and include Crohn’s disease (CD) and Ulcerative Colitis (UC). The pathogenesis is not known, but involves at least in part a loss of tolerance towards the commensal colonic microbiota. READ MORE
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4. Organ-specific mechanisms of vascular development in the mesentery
Abstract : Understanding how the vascular systems are formed has significant clinical importance. General mechanisms underlying vascular development have been extensively studied during the past decades. However, the mechanisms regulating the development and function of the blood and lymphatic vessels in specific organs are poorly understood. READ MORE
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5. Innate immune cell response in sepsis
Abstract : Leukocyte recruitment is known to be a key feature at sites of inflammation and important in the combat against infectious agents. However, the mechanisms of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation remain elusive. READ MORE