Search for dissertations about: "platelet-derived growth factor"

Showing result 6 - 10 of 148 swedish dissertations containing the words platelet-derived growth factor.

  2. 6. Pericyte recruitment and functions in vivo. Studies of platelet-derived growth factor-B deficient embryos

    Author : Mats Hellström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mouse; gene targeting; platelet-derived growth factor; pericyte; vascular smooth muscle; angiogenesis;

    Abstract : A functional vascular system is essential for tissue growth and maintenance, and the circulatory system is therefore the first operational organ of the vertebrate embryo. In conditions of pathological tissue growth, such as tumors, formation of new blood vessels is also required, and it is anticipated that prevention of blood vessel development in those settings might ameliorate the disease progress. READ MORE

  4. 7. Regulation of the platelet-derived growth factor β-receptor

    Author : Catrin Molander; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; inflammation; TNF-a; tyrosine kinase; medulloblastoma; Myc; NF-Y; Sp1;

    Abstract : Growth factors are important signalling molecules, regulating cell growth, as well as cell movement, differentiation and apoptosis. They bind to specific receptors on the cell surface causing activation of the receptors. Activated receptors then attract adaptor molecules that brings the signal further into the cell. READ MORE

  5. 8. Functional Studies of Collagen-Binding Integrins α2β1 and α11β1 : Interplay between Integrins and Platelet-Derived Growth Factor Receptors

    Author : Gunilla Grundström; Kristofer Rubin; Karl-Eric Magnusson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Integrins are heterodimeric cell surface receptors, composed of an α- and a β-subunit, which mediate cell-extracellular matrix (ECM) interactions. Integrins mediate intracellular signals in response to extracellular stimuli, and cooperate with growth factor and other cytokine receptors. READ MORE

  6. 9. Structural and functional studies of platelet-derived growth factor

    Author : Maria Andersson; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  7. 10. Role of platelet-derived growth factor in neoplastic transformation

    Author : Christer Betsholtz; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE