Search for dissertations about: "plectin"
Found 3 swedish dissertations containing the word plectin.
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1. The muscle cytoskeleton of mice and men : Structural remodelling in desmin myopathies
Abstract : The muscle fibre cytoskeleton of skeletal and heart muscle cells is composed mainly of intermediate filaments (IFs), that surround the myofibrils and connect the peripheral myofibrils with the sarcolemma and the nuclear membrane. Desmin is the first muscle specific IF protein to be produced in developing muscles and is the main IF protein in mature muscles. READ MORE
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2. Molecular analysis of the FET family fusion oncoprotein FUS-DDIT3
Abstract : Chromosomal translocations leading to formation of tumor type specific fusion oncogenes are frequently found in human cancers. The FET family genes (FUS, EWSR1 and TAF15) occur in translocations with genes encoding various transcription factors in sarcomas and leukemias. READ MORE
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3. Genetic studies of zebrafish muscles : clues to protection in muscle disease
Abstract : Muscular dystrophies (MDs) are caused by dysregulation of over 40 proteins but commonly share features of muscle weakness, myofiber death and regeneration, loss of ambulation and premature death. A MD involves a broken link anywhere in the connection from extracellular matrix through the sarcolemma to the sarcomere. READ MORE