Search for dissertations about: "pneumococcal polysaccharide vaccine"

Showing result 1 - 5 of 13 swedish dissertations containing the words pneumococcal polysaccharide vaccine.

2. 1. Infectious and bleeding complications in patients with hematological malignancies : Studies on diagnosis and prevention

   Author : Tobias Svensson; Honar Cherif; Martin Höglund; Jan Sjölin; Christine Wennerås; Uppsala universitet; []
   Keywords : Chronic lymphocytic leukemia; Immunodeficiency; Hypogammaglobulinemia; IgG subclass; Pneumococci; Pneumococcal vaccine; Polysaccharide vaccine; Protein-conjugate vaccine; Aspergillosis; Bronchoalveolar lavage; Invasive fungal disease; Pneumocystis jirovecii pneumonia; Myelodysplastic syndrome; Azacitidine; Eltrombopag; Thrombocytopenia; Thrombopoietin receptor; Oncology; Onkologi;

   Abstract : The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS).Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. READ MORE

4. 2. Impact of the inflammatory response on specific immunity in neurosurgical patients

   Author : Anna Ljunghill Hedberg; Jan Sjölin; Karlis Pauksen; Lars Hagberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T-cell-dependent vaccine; T-cell-independent vaccine; CNS injury-induced immune deficiency syndrome; pneumococcal conjugate vaccine; pneumococcal polysaccharide vaccine; posttraumatic meningitis.; Medicinsk vetenskap; Medical Science; Infektionssjukdomar; Infectious Diseases;

   Abstract : Vaccination with a T-cell-dependent pneumococcal conjugate vaccine (PCV) followed by a T-cell-independent pneumococcal polysaccharide vaccine (PPSV) is recommended after basilar skull fracture to reduce the risk of meningitis. The optimal time frame for vaccination has not yet been established and varies widely in practice. READ MORE

5. 3. Pneumococcal vaccination in inflammatory rheumatic disease and in splenectomy patients. From antibody response to memory cells

   Author : Per Nived; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pneumokockvaccin; konjugerat; Pneumokockpolysackaridvaccin; Inflammatorisk reumatisk sjukdom; Antikroppssvar; Minnesceller; Splenektomi; Pneumococcal conjugate vaccine; Pneumococcal polysaccharide vaccine; rheumatic diseases; antibody response; Splenectomy; memory cells;

   Abstract : Objectives:The overall aim of the dissertation is to examine antibody response to immunization with pneumococcal vaccine in patients with inflammatory rheumatic disease (IRD), in relation to disease-modifying antirheumatic drug (DMARD) treatments, and in postsplenectomy patients.Methods:(I) Splenectomized patients without previous pneumococcal conjugate vaccine (PCV) immunization were invited to receive one dose 13-valent PCV (PCV13). READ MORE

6. 4. Invasive Pneumococcal Infections

   Author : Erik Backhaus; Göteborgs universitet; []
   Keywords : Streptococcus pneumoniae; epidemiology; risk factors; pneumonia; meningitis; serotype; clonal complex;

   Abstract : Streptococcus pneumoniae is a major cause of disease, ranging from uncomplicated respiratory infections to severe invasive pneumococcal disease (IPD), including bacteraemic pneumonia, septicaemia with unknown focus and meningitis. Case fatality rate (CFR) remains high and antibiotic resistance is increasing globally. S. READ MORE

7. 5. Infectious immunity and pneumococcal vaccine responses in multiple myeloma and related disorders

   Author : Johanna Karlsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; multiple myeloma; Waldenstrom s macroglobulinemia; MGUS; elderly; immunity; infection; pneumococcal vaccination; ELISA; opsonophagocytosis;

   Abstract : Multiple myeloma (MM), Waldenstrom’s macroglobulinemia (WM), and monoclonal gammopathy of undetermined significance (MGUS) are B cell conditions associated with suppressed immune functions and susceptibility to infection. Severe pneumococcal disease is common not least in MM patients and vaccination is considered important, although the protective efficacy is debated. READ MORE