Search for dissertations about: "pocket cavity"

Showing result 1 - 5 of 11 swedish dissertations containing the words pocket cavity.

  2. 1. Investigations of Heat Transfer and Fluid Flow in the Pocket Region of a Gas Turbine Engine and Cooling of a Turbine Blade

    Author : Jian Liu; Värmeöverföring; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; pocket cavity; symmetric vane; Liquid Crystal Thermography; truncated ribs; staggered arrangement; perforated ribs; secondary flows; endwall film cooling; leading edge; turbine vane; coolant coverage;

    Abstract : In the present work, heat transfer within gas turbine applications are investigated bothexperimentally and numerically. The main content concerns heat transfer and fluidflow over the pocket region and cooling of a turbine blade. READ MORE

  4. 2. Protein interactions involved in alphavirus assembly

    Author : Ulrica Skoging Nyberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alphavirus; Semliki Forest Virus; Virus assembly; Capsid Protein; Nucleocapsid; Viral Envelope Proteins;

    Abstract : Viruses have to protect their genomes during transport from the infected to an uninfected host cell. This is achieved by forming a protein shell around the nucleic acid. Virus assembly is a complex process that involves interactions with the viral genome, the viral structural proteins and for enveloped viruses a lipid membrane. READ MORE

  5. 3. Structure-Function Relationships of Pi Class Glutathione Transferase Studied by Protein Engineering

    Author : Usama M. Hegazy; Bengt Mannervik; Mikael Widersten; T. J. Mantle; Uppsala universitet; []
    Keywords : Biochemistry; Glutathione transferase; targeted chemical modification; lock-and-key motif; cooperativity; stucture-function relationship; protein engineering; unnatural amino acid; site-specific mutation; Biokemi;

    Abstract : The glutathione transferases (GSTs) represent a superfamily of dimeric proteins involved in cellular detoxication by catalyzing the nucleophilic addition of the reduced glutathione (GSH) to the hydrophobic electrophiles. The present work focuses on the functional role of the conserved structures of GSTP1-1. READ MORE

  6. 4. X-ray structure analysis of short-chain dehydrogenases/reductases

    Author : Jordi Benach-Andreu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : crystal structure; short-chain dehydrogenases reductases; Drosophila alcohol dehydrogenase; catalytic reaction mechanism; Comamonas testosteroni 3[beta] 17[beta]hydroxysteroid dehydrogenase;

    Abstract : X-ray crystallography and site-directed mutagenesis were used to better understand the structure/function relationships in the family of short-chain dehydrogenases/reductases (SDR). This group of enzymes constitutes a protein family with at least 60 members with highly diverse functions in pro- and eukaryotes. READ MORE

  7. 5. Molecular characterisation of major allergens from mite (Lep d 2) and cat (Fel d 1)

    Author : Liselotte Kaiser; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Allergens allergy; cat; mite; immunotherapy; recombinant allergens.;

    Abstract : The prevalence of allergic disease has increased significantly during the last decades and today more than 30% of the Swedish population is affected. By using recombinant allergens, diagnostics and treatment can be improved and the mechanisms of allergic reactions may be further explored. READ MORE