Search for dissertations about: "podocyte"

Showing result 21 - 25 of 33 swedish dissertations containing the word podocyte.

  2. 21. Permeability of the glomerular filtration barrier in relation to the size, shape, charge and deformability of the permeating molecules

    Author : Daniel Asgeirsson; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteinuria; capillary physiology; peritoneal membrane; dialysis; microalbuminuria; cardiovascular; endothelial dysfunction; diagnosis;

    Abstract : Characterization of the glomerular filtration barrier is of fundamental importance for understanding the pathophysiology of proteinuric kidney diseases. Furthermore, it can be of key value in the understanding of microalbuminuria, which is often associated with endothelial dysfunction in conjunction with cardiovascular disease. READ MORE

  4. 22. High-resolution imaging of kidney tissue samples

    Author : David Unnersjö-Jess; Hans Blom; Lena Scott; Hjalmar Brismar; Peter Hansell; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Super Resolution Microscopy; Kidney; Imaging; Fluorescence; Kidney development; Calcium; Biological Physics; Biologisk fysik;

    Abstract : The kidney is one of the most important and complex organs in the human body, filtering hundreds of litres of blood daily. Kidney disease is one of the fastest growing causes of death in the modern world, and this motivates extensive research for better understanding the function of the kidney in health and disease. READ MORE

  5. 23. Nephrin-mutations in congenital nephrotic syndrome of the Finnish type and cell lineage specific gene regulation

    Author : Olga Beltcheva; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Nephrin; NPHS 1; CNF; podocytes; promoter;

    Abstract : Kidneys, the main excretory organs in vertebrates, play central role in removing water soluble metabolic waste products from the organism. Many acquired and inherited renal diseases in man lead to kidney dysfunction and nephrotic syndrome - life-threatening condition affecting increasing number of people in the modem society. READ MORE

  6. 24. The role of melanocortin 1 receptor in kidney disease

    Author : Annika Lindskog Jonsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrotic syndrome; proteinuria; adrenocorticotropic hormone; melanocortin 1 receptor; podocytes;

    Abstract : Nephrotic syndrome is a term describing a group of poorly understood glomerular diseases that are responsible for a steadily increasing number of patients requiring active uremic care. Characteristic symptoms of nephrotic syndrome are proteinuria, hypoalbuminemia, hyperlipidemia and peripheral edema, and treatment of these symptoms, rather than their cause, is currently the only option available to the clinician. READ MORE

  7. 25. Nephrin cellular trafficking and intracellular interactions

    Author : Xiao Li Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Nephrin; signal; missense mutations; trafficking.;

    Abstract : Nephrin is a 180-kDa transmembrane glycoprotein belonging to the immunoglobulin family of cell adhesion molecules. Nephrin has an extracellular part with eight Ig-like motifs, one fibronectin-like domain, a transmembrane region and a short cytoplasmic tail. READ MORE