Search for dissertations about: "poly A -specificity"

Showing result 1 - 5 of 693 swedish dissertations containing the words poly A -specificity.

  2. 1. Optical Modeling and Characterization of Layers and Multilayer Structures : Organic Optoelectronic Devices and Spectroscopic Ellipsometry

    Author : Leif A. A. Pettersson; Robert W. Collins; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This dissertation is on the subject of modeling and characterization of layers and multilayer structures with respect to their optical properties and characteristics. A number of different systems have been investigated; among them multilayer structures in the form of organic optoelectronic devices, anisotropic layers of conjugated polymers as well as inhomogeneous layers of porous silicon and oxidized silver. READ MORE

  4. 2. Covalent Vapor-Phase Grafting of Degradable Polymers

    Author : Martina Källrot; Ann-Christine Albertsson; Maria Nowokowska; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Vapor-phase grafting; covalent surface modification; functionalization; solvent-free grafting; sub-micron patterned topography; scaffolds; degradable polymers; poly L-lactide ; poly ε-caprolactone ; poly trimethylene carbonate ; poly L-lactide-co-glycolide ; poly 1; 5-dioxepan-2-one-co-L-lactide ; poly ε-caprolactone-co-L-lactide ; N-vinylpyrrolidone; maleic anhydride; acrylamide; acrylic acid; hyaluronic acid; in vitro degradation; Gasfasympning; kovalent ytmodifiering; funktionalisering; lösningsmedelsfri ympning; sub-micrometer mönstrad topografi; nedbrytbara polymerer; poly L-laktid ; poly ε-kaprolakton ; poly trimetylen karbonat ; poly L-laktid-co-glykolid ; poly 1; 5-dioxepan-2-one-co-L-laktid ; poly ε-kaprolakton-co-L-laktid N-vinylpyrrolidon; maleinsyraanhydrid; akrylamid; akrylsyra; hyaluronsyra; in vitro nedbrytning; Polymer chemistry; Polymerkemi;

    Abstract : Gasfasympning är en del i den moderna strategin för optimering av den molekylära designen av biomaterial. Kovalent ytmodifiering med hydrofila vinylmonomerer och koppling med bioaktiva grupper används för att öka biokompatibiliteten och bioaktiviteten hos biomaterialen.. READ MORE

  5. 3. Covalent Surface Modification of Degradable Polymers for Increased Biocompatibility

    Author : Martina Källrot; Ann-Christine Albertsson; Mikael Lindström; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Vapor phase grafting; covalent surface modification; solvent free; nano patterned topography; degradable polymers; poly ε-caprolactone ; poly L-lactide ; poly lactide-co-glycolide ; poly trimethylene carbonate ; N-vinylpyrrolidone; maleic anhydride; acrylamide; Gasfasympning; kovalent ytmodifiering; lösningsmedelsfri; nedbrytbara polymerer; nanomönstrad topografi; poly L-laktid ; poly ε-kaprolakton ; poly laktid-co-glykolid ; poly trimetylen karbonat ; N-vinylpyrrolidon; maleinsyraanhydrid; akrylamid; Polymer chemistry; Polymerkemi;

    Abstract : Degradable polymers have gained an increased attention in the field of biomedical applications over the past decades, for example in tissue engineering. One way of improving the biocompatibility of these polymers is by chemical surface modification, however the risk of degradation during the modification procedure is a limiting factor. READ MORE

  6. 4. Functional Significance of Multiple Poly(A) Polymerases (PAPs)

    Author : Helena Nordvarg; Claire Moore; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; poly A polymerase; PAP; phosphorylation; isoforms; alternative splicing; kinetic parameters; hyperphosphorylation; regulation; Genetik; Poly A polymeras; PAP; fosforylering; isoformer; alternativ splitsning; kinetiska parametrar; reglering; Clinical genetics; Klinisk genetik; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : 3’ end cleavage and polyadenylation are important steps in the maturation of eukaryotic mRNAs. Poly(A) polymerase (PAP), the enzyme catalysing the addition of adenosine residues, exists in multiple isoforms. In this study the functional significance of multiple poly(A) polymerases have been investigated. READ MORE

  7. 5. Poly(A)-Specific Ribonuclease (PARN)

    Author : Yan-Guo Ren; Eric Westhof; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Poly A -specific ribonuclease; PARN; deadenylation; processive; oligomeric; cap interacting; aminoglycoside; active site; FE2 -mediated cleavage; metal ion switch; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Degradation of the mRNA 3'-end located poly(A) tail is an important step for mRNA decay in mammalian cells. Thus, to understand mRNA decay in detail, it is important to identify the catalytic activities involved in degrading poly(A). READ MORE