Search for dissertations about: "polycystic ovary syndrome"

Showing result 16 - 20 of 41 swedish dissertations containing the words polycystic ovary syndrome.

2. 16. Mass Spectrometric Applications for Diagnosing Metabolic and Endocrine Diseases

   Author : Mark M. Kushnir; Jonas Bergquist; Alan L Rockwood; David Herold; Uppsala universitet; []
   Keywords : Analytical chemistry; biomarker; liquid chromatography; tandem mass spectrometry; LC-MS MS; sample preparation; isomers; steroid hormones; congenital adrenal hyperplasia; polycystic ovary syndrome; Analytisk kemi;

   Abstract : Disease-specific compounds (biomarkers) are analyzed in clinical laboratories to assist with diagnosing diseases. This thesis describes development and validation of liquid chromatography tandem mass spectrometry (LC-MS/MS) based tests for diagnosing a diverse group of endocrine and metabolic diseases. READ MORE

4. 17. Studies of hyperandrogenicity and the metabolic syndrome in premenopausal women

   Author : Fariba Baghaei; Göteborgs universitet; []
   Keywords : androgens; SHBG; HPA axis; abdominal obesity; insulin; HDL; metabolic syndrome; ovarian volume; PCOS; polymorphism; genetics; androgen receptor; estrogen receptor; aromatase;

   Abstract : An androgenic sex hormone profile appears to be a typical feature of the metabolic syndrome (MetS) and a powerful risk factor for the development of type 2 diabetes in women. The causes of relative hyperandrogenicity (HA) are not clearly defined. READ MORE

5. 18. Developmental origins of polycystic ovary syndrome : role of early adverse life events on adult health

   Author : Maria Manti; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The research focus of this thesis is polycystic ovary syndrome (PCOS), the most common endocrine disorder among women of reproductive age, associated with reproductive, cardio-metabolic, and mental health complications. Despite the high prevalence, little is known about the etiology of the syndrome. READ MORE

6. 19. Polycystic ovary syndrome : a study of adipocyte lipolysis in relation to endocrine and metabolic status

   Author : Ingvar Ek; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Adipocyte; beta-adrenoceptors; FFA; hyperandrogenism; HSL; insulin resistance; lipolysis; PCOS; PKA;

   Abstract : The aim of the present thesis was to obtain insight into possible regulatory effects of androgens on the regulation of lipolysis in subcutaneous as well as visceral adipose tissue in women with the polycystic ovary syndrome (PCOS). In non-obese women with PCOS, adrenergic lipolysis was investigated in both subcutaneous abdominal and visceral adipose tissue and several, novel disturbances were found. READ MORE

7. 20. Polycystic ovary syndrome (PCOS) : role of androgens and obesity on placental function and fetal development

   Author : Romina Fornes; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting women in childbearing age with a prevalence of up to 17.8%. The syndrome is characterized by hyperandrogenism, irregular cycles and polycystic ovaries. The etiology of PCOS is unclear, but it is thought to be multifactorial. READ MORE