Search for dissertations about: "polylysine"

Found 5 swedish dissertations containing the word polylysine.

  1. 1. Pretargeting agents and At-211-labeled effector molecules: Synthesis and preclinical evaluation for pretargeted alpha-radioimmunotherapy

    Author : Sofia Frost; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha particles; astatine-211; avidin; biotin; ovarian cancer; polylysine; pretargeted radioimmunotherapy;

    Abstract : .... READ MORE

  2. 2. Development of targeted alpha therapy with Bi-213 and At-211 for the treatment of disseminated cancer

    Author : Anna Gustafsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha particles; astatine; bismuth; MX35; ovarian cancer; polylysine; pretargeted radioimmunotherapy; radioimmunotherapy;

    Abstract : Radioimmunotherapy (RIT) is a type of targeted cancer therapy. The concept behind RIT is to deliver cytotoxic ionizing radiation to tumor cells by attaching radionuclides to tumor-specific antibodies. READ MORE

  3. 3. PREVENTION OF POSTSURGICAL ABDOMINAL ADHESIONS BY POLYPEPTIDES

    Author : Laszlo Nehéz; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Surgery; orthopaedics; poly-L-glutamate; anastomotic healing; peritoneum; adhesion; prevention; poly-L-lysine; traumatologi; Kirurgi; ortopedi; polypeptides; surgery;

    Abstract : Peritoneal adhesions develop after almost all abdominal surgical interventions and represent an important cause of postoperative intestinal obstruction, abdominal discomfort and infertility. Postoperative adhesions can potentially be reduced by using different antiadhesive agents. READ MORE

  4. 4. Quantitation, Purification and Reconstitution of the Red Blood Cell Glucose Transporter GLUT1

    Author : Shusheng Zuo; Bengt Mannervik; Bengt Persson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Cholesterol; Cytochalasin B; Glucose; GLUT1; Hummel and Dreyer analysis; Immobilization; PEG 5000 -DSPE; Biomembrane; Proteoliposome; Quantitative frontal affinity chromatography; Red blood cell streptavidin-biotin immobilization; Sulfhydryl affinity chromatography; The modified micro-Bradford CaPE assay; MALDI-ToF-MS; Biokemi; Biochemistry; Biokemi;

    Abstract : The human glucose transporter GLUT1 facilitates glucose to be accumulated on the other side of the cell membrane. The functional state of GLUT1 is uncertain due to diversity of the reports. In this thesis, the activity of red blood cell GLUT1 was extensively studied to further characterize this protein. READ MORE

  5. 5. Small bowel obstruction and toxicity of a new model of adhesion prevention

    Author : Karolin Isaksson; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small bowel obstruction; predictive parameters; appendectomy; open versus laparoscopic; abdominal adhesions; prevention; polypeptides; toxicity; biodistribution;

    Abstract : Abstract Background: Small bowel obstruction (SBO) is a common surgical diagnosis. If no signs of strangulation are evident, the majority of the patients can be conservatively managed. Approximately one third of the patients need surgical treatment and there is a need for early parameters that can predict operative intervention. READ MORE