Search for dissertations about: "polymers and drug delivery thesis"

Showing result 1 - 5 of 52 swedish dissertations containing the words polymers and drug delivery thesis.

2. 1. Synthesis of Polymeric Nanocomposites for Drug Delivery and Bioimaging

   Author : Heba Asem; Joydeep Dutta; Moustapha Hassan; Fei Ye; Jöns Hilborn; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; QDs; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; biodistribution; Fysik; Physics;

   Abstract : Nanomaterials have gained great attention for biomedical applications due to their extraordinary physico-chemical and biological properties. The current dissertation presents the design and development of multifunctional nanoparticles for molecular imaging and controlled drug delivery applications which include biodegradable polymeric nanoparticles, superparamagnetic iron oxide nanoparticles (SPION)/polymeric nanocomposite for magnetic resonance imaging (MRI) and drug delivery, manganese-doped zinc sulfide (Mn:ZnS) quantum dots (QDs)/ SPION/ polymeric nanocomposites for fluorescence imaging, MRI and drug delivery. READ MORE

4. 2. Development and characterization of an in vitro method for interaction studies between polymers and pharmaceuticals : Aiding in the development of new drug delivery systems

   Author : Marcus Wanselius; Per Hansson; Magnus Bergström; Susanna Abrahmsén-Alami; Christian Pedersen; Anna Fureby; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microgels; Subcutaneous administration; Drug delivery; Microfluidics; In vitro methodology; Method development; Biopharmaceuticals; Amphiphilic drugs; Polyelectrolytes; Hyaluronic acid; Peptides; Farmaceutisk fysikalisk kemi; Pharmaceutical Physical Chemistry;

   Abstract : Polymers are a group of macromolecules used in formulations of pharmaceuticals, one example being the delivery system DC Bead™. Further, some of the most abundant and for drug delivery important constituents of the subcutaneous tissue are charged polymers (polyelectrolytes), e.g. collagen, hyaluronic acid, and chondroitin sulfate. READ MORE

5. 3. Hydrogels of Poly(vinyl alcohol) and Nanocellulose for Ophthalmic Applications : Synthesis, Characterization, Biocompatibility and Drug Delivery Studies

   Author : Gopi Krishna Tummala; Albert Mihranyan; Natalia Ferraz; Cecilia Persson; Jonas Lindh; Che Connon; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanocellulose; poly vinyl alcohol ; hydrogel; cornea regeneration; therapeutic lens; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

   Abstract : Hydrogels are commonly used materials in ophthalmic care as contact lenses, bandage lenses, corneal implants, and cornea regeneration scaffolds. Hydrogels can be produced by physical, chemical, or radiation crosslinking of hydrophilic polymers. READ MORE

6. 4. Drugs and polymers in dissolving solid dispersions : NMR imaging and spectroscopy

   Author : Carina Dahlberg; István Furó; Anna Millqvist-Fureby; Michael Schuleit; Jadwiga Tritt-Goc; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical chemistry; Fysikalisk kemi; Surface and colloid chemistry; Yt- och kolloidkemi; PHARMACY; FARMACI;

   Abstract : The number of poorly water-soluble drug substances in the pharmaceutical pipeline is increasing, and thereby also the need to design effective drug delivery systems providing high bioavailability. One favourable formulation approach is preparation of solid dispersions, where dispersing a poorly water-soluble drug in a water-soluble polymer matrix improves the dissolution behaviour and the bioavailability of the drug. READ MORE

7. 5. Diffusion Controlled Drug Release from Slurry Formed, Porous, Organic and Clay-derived Pellets

   Author : Erik Jämstorp Berg; Maria Strømme; Håkan Engqvist; Susanne Bredenberg; Pentti Tengvall; Nanoteknologi och funktionella material Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffusion; Drug delivery; Antithrombotic drugs; Highly potent opioids; Modeling; Clays; Polymers; Pellets; Beads; Materialvetenskap; Materials Science;

   Abstract : Coronary artery disease and chronic pain are serious health issues that cause severe discomfort and suffering in society today. Antithrombotic agents and highly potent analgesics play a critical role in improving the recovery process for patients being treated for these diseases. READ MORE