Search for dissertations about: "polymers as drug delivery"

Showing result 1 - 5 of 40 swedish dissertations containing the words polymers as drug delivery.

  1. 1. Synthesis of Polymeric Nanocomposites for Drug Delivery and Bioimaging

    University dissertation from KTH Royal Institute of Technology

    Author : Heba Asem; Joydeep Dutta; Moustapha Hassan; Fei Ye; Jöns Hilborn; [2016]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; QDs; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; biodistribution; Physics; Fysik;

    Abstract : Nanomaterials have gained great attention for biomedical applications due to their extraordinary physico-chemical and biological properties. The current dissertation presents the design and development of multifunctional nanoparticles for molecular imaging and controlled drug delivery applications which include biodegradable polymeric nanoparticles, superparamagnetic iron oxide nanoparticles (SPION)/polymeric nanocomposite for magnetic resonance imaging (MRI) and drug delivery, manganese-doped zinc sulfide (Mn:ZnS) quantum dots (QDs)/ SPION/ polymeric nanocomposites for fluorescence imaging, MRI and drug delivery. READ MORE

  2. 2. Diffusion Controlled Drug Release from Slurry Formed, Porous, Organic and Clay-derived Pellets

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Jämstorp Berg; Maria Strømme; Håkan Engqvist; Susanne Bredenberg; Pentti Tengvall; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffusion; Drug delivery; Antithrombotic drugs; Highly potent opioids; Modeling; Clays; Polymers; Pellets; Beads; Materialvetenskap; Materials Science;

    Abstract : Coronary artery disease and chronic pain are serious health issues that cause severe discomfort and suffering in society today. Antithrombotic agents and highly potent analgesics play a critical role in improving the recovery process for patients being treated for these diseases. READ MORE

  3. 3. Dendrimer-mediated gene delivery: Effect of polymer structure on cellular response

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kristina Fant; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene therapy; DNA condensation; cationic polymers; toxicity; non-viral vector; drug delivery; polyplex; PAMAM dendrimers;

    Abstract : The delivery of nucleic acids to cells, in vitro and in vivo, is becoming a realistic approach for intervention with gene expression at a molecular level. It can be used to repair malfunctioning genes or to introduce new functionalities, with the most important application being clinical treatment of human diseases. READ MORE

  4. 4. Environment-Sensitive Multifunctional Drug Delivery Systems

    University dissertation from Stockholm : KTH

    Author : Jian Qin; Mamoun Muhammed; Marcus Textor; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TECHNOLOGY Chemical engineering Chemical process and manufacturing engineering Materials chemistry; TEKNIKVETENSKAP Kemiteknik Kemisk process- och produktionsteknik Materialkemi;

    Abstract : Drug delivery systems (DDS) with multiple functionalities such as environment-sensitive drug release mechanisms and visualization agents have motivated the biomedical community as well as materials chemists for more than a decade. This dissertation is concerned with the development of nanoparticles for multifunctional DDS  to tackle several crucial challenges in these complex systems, including polymeric nanospheres which respond to temperature change, superparamagnetic iron oxide nanoparticles/polymeric composite for magnetic resonance imaging contrast agents and drug carriers, immunoresponse of nanomaterials and injectable magnetic field sensitive ferrogels. READ MORE

  5. 5. Synthesis, Characterisation and Properties of Biomimetic Biodegradable Polymers

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Fredrik Nederberg; Tim Bowden; Nicola Tirelli; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; biodegradable polymers; biomimetic; phospholipid-like; phosphorylcholine; amphiphilic; ionomer; hemocompatible; non-adhesive; water uptake; reduced protein adsorption; protein delivery; Kemi; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi;

    Abstract : The acceptance of blood contacting implants creating favorable conditions in vivo is decisively determined by their interaction with proteins that mediate inter cellular interactions with synthetic substrates. Adsorbed proteins can activate blood cascade systems like coagulation and complement that may result in serious blood clots, and/or immunological reactions. READ MORE