Search for dissertations about: "polyol pathway"

Found 2 swedish dissertations containing the words polyol pathway.

  2. 1. Diabetes-induced Alterations in Renal Microcirculation and Metabolism

    Author : Fredrik Palm; Per Liss; Peter Hansell; Per-Ola Carlsson; Gerald DiBona; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; diabetes mellitus; kidney; nephropathy; oxygen tension; haemodynamic; nitric oxide; oxygen consumption; radical oxygen species; polyol pathway; Fysiologi; Physiology; Fysiologi;

    Abstract : Diabetes-induced renal complications, i.e. diabetes nephropathy, are a major cause of morbidity and mortality. The exact mechanism mediating the negative influence of hyperglycaemia on renal function is unclear, although several hypotheses have been postulated. READ MORE

  4. 2. Pathomechanism of diabetic nephropathy

    Author : Anna Körner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : diabetic nephropathy; hyperflltration; Na ; K - ATPase; Dahl rats; salt sensitive hypertension; glomerulosclerosis; polyol pathway activation; oxidative stress;

    Abstract : Diabetic nephropathy is today the most common cause of end stage renal failure. The risk for developing overt diabetic nephropathy is considerably reduced by antihypertensive treatment, and adequate control of blood glucose. However, there is a need for additional and even more efficient tools to prevent this complication of diabetes. READ MORE