Search for dissertations about: "poor-prognosis"

Showing result 11 - 15 of 329 swedish dissertations containing the word poor-prognosis.

  2. 11. Hodgkin Lymphoma – an Interplay Between Tumour Cell and Microenvironment

    Author : Ingrid Glimelius; Gunilla Enblad; Daniel Molin; Rose-Marie Amini; Marie Fischer; Volker Diehl; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN; Oncology; onkologi;

    Abstract : Hodgkin lymphoma (HL) is a malignant disorder characterised by few tumour cells surrounded by a massive infiltrate of inflammatory cells, fibrosis, and microvessels. Therefore, it is a good model in which to study the interplay between tumour cells and the microenvironment. READ MORE

  4. 12. Mantle cell lymphoma strategies in primary treatment

    Author : Alexandra Albertsson Lindblad; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mantle cell lymphoma; registry data; Clinical Trial; Phase I; Clinical Trial; Phase II; rituximab; bendamustine; lenalidomid; ibrutinib; ADCC; in vitro model; TP53 mutations; watchful waiting; mantle cell lymphoma; real-world data; lenalidomide; rituximab; bendamustin; ibrutinib; ADCC; TP53 mutation; CDKN2A; NGS; MIPI; Watchful waiting;

    Abstract : Mantle cell lymphoma (MCL) is associated with poor prognosis due to an aggressive clinical course. Being a rare disease, there are few randomized trials in MCL and there is no defined golden standard in primary treatment. READ MORE

  5. 13. Epidemiological studies in de novo and secondary acute leukemia

    Author : Erik Hulegårdh; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute leukemia; ALL; AML; adult; Secondary acute leukemia; MDS; MPN;

    Abstract : Abstract Background Acute leukemia (AL) is a rare blood cancer with poor prognosis in adult patients. Socioeconomic factors are known to impact cancer outcomes, but have not been adequately examined among adult AL patients. READ MORE

  6. 14. Bystander Cells and Prognosis in Hodgkin Lymphoma

    Author : Daniel Molin; Stephen J. Proctor; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin Lymphoma; Bystander cells; Eosinophilic granulocytes; Eosinophil cationic protein ECP ; Mast cells; Prognosis; Early and Intermediate stage; Onkologi; Hodgkin lymfom; eosinofila granulocyter; ECP; mast celler; prognos; tidiga och intermediära stadier; Oncology; Onkologi; Oncology; onkologi;

    Abstract : Hodgkin lymphoma (HL) is characterised histologically by a minority of malignant Hodgkin and Reed-Sternberg (HRS) cells surrounded by benign cells, and clinically by a relatively good prognosis. The treatment, however, leads to a risk of serious side effects. READ MORE

  7. 15. MicroRNA expression profiles in prostate cancer bone metastases : functional effects of microRNA-23c, -375, and -4328

    Author : Helena Järemo; Pernilla Wikström; Maria Brattsand; Anders Bergh; Elin Thysell; Guido Jenster; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer bone metastases; microRNA; metastatic subtypes; extracellular vesicles; Pathology; patologi;

    Abstract : Non-coding microRNAs (miRNAs) function as post-transcriptional regulators of gene expression by interacting with messenger RNA. Dysregulation of miRNAs has many possible consequences, including tumor-suppressive or -promoting ones, and restoring or preventing the effects of miRNA alteration has therapeutic potential. READ MORE