Search for dissertations about: "poor-prognosis"
Showing result 6 - 10 of 329 swedish dissertations containing the word poor-prognosis.
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6. Protein Expression Profiling of Cancer Biomarkers
Abstract : The Human Protein Atlas project is a Swedish research initiative that uses antibody-based proteomics for large scale protein profiling in human tissues and cells. Affinity-purified antibodies are produced within the project and used for immunohistochemical staining on tissue micro arrays (TMAs) in order to map the human proteome and publish the result in a protein atlas (www. READ MORE
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7. Hepatic and Peritoneal Colorectal Metastases : Aspects of Prognosis and Treatment
Abstract : Although two-thirds of colorectal cancer patients are cured by surgery, approximately 50% of the patients with this disease develop locally recurrent or distant metastases during the course of their illness. The aim of this study was to identify metastatic sites associated with poor prognosis in rectal cancer and then to investigate methods that can prevent the development and growth of metastases and optimise uptake of drugs at these sites in animal models. READ MORE
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8. Novel Regulators of Brain Tumor Development : – From neural stem cell differentiation to in vivo models
Abstract : Malignant brain tumors are diseases with poor prognosis and/or severe long-term side effects of treatment. This thesis aimed to discover novel regulators in brain tumor development, based on studying neural stem cell and progenitor cell (NSPC) differentiation and using animal models to introduce new insights to mechanisms of human brain tumors. READ MORE
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9. Immunohistochemical and molecular studies on ovarian cancer progression and prognosis
Abstract : Epithelial ovarian cancer (EOC) is the most lethal malignancy of the female reproductive tract. Due to vague symptomatology, the majority of EOC patients are diagnosed in advanced clinical stages with poor survival rates, despite improvements in surgical techniques and the advent of targeted therapeutics. READ MORE
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10. Body constitution, statin use, and tumor characteristics. Implications for prognosis
Abstract : Breast cancer is an important cause of disease-burden and death in women. To prevent over- and undertreatment of breast cancer patients, new prognostic and predictive factors are needed. READ MORE