Search for dissertations about: "porous drug delivery"

Showing result 1 - 5 of 19 swedish dissertations containing the words porous drug delivery.

2. 1. Porous Amorphous Calcium Carbonate and Phosphate : Synthesis and Application

   Author : Rui Sun; Ocean Cheung; Maria Strømme; Ken Welch; Denis Gebauer; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; amorphous calcium carbonate; amorphous calcium phosphate; stabilization; crystallization; porous material; drug delivery; gas adsorption; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

   Abstract : The synthesis of porous amorphous calcium carbonate (ACC) and porous amorphous calcium phosphate (ACP) was developed in this thesis. Porous ACC with specific Brunauer–Emmett–Teller (BET) surface area of >350 m2/g was synthesized using a surfactant free approach. The high surface area of porous ACC was related to its nanostructure. READ MORE

4. 2. Structure evolution of phase-separated EC/HPC films for controlled drug release

   Author : Pierre Carmona; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electron microscopy; coarsening; cellulose; phase separation kinetics; drug delivery; phase separation mechanisms; porous film; biopolymer; controlled drug release; confocal laser scanning microscope; spin-coating.;

   Abstract : Porous phase-separated ethylcellulose/hydroxypropylcellulose (EC/HPC) films are used to control drug transport out of pharmaceutical pellets. The drug transport rate is determined by the structure of the porous films that are formed as the water-soluble HPC leaches out. READ MORE

5. 3. Structure evolution of spin-coated phase separated EC/HPC films

   Author : Pierre Carmona; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; spin-coating; controlled drug release; porous film; drug delivery; confocal laser scanning microscope; kinetics; phase separation mechanisms; cellulose; biopolymer; phase separation;

   Abstract : Porous phase-separated films made of ethylcellulose (EC) and hydroxypropylcellulose (HPC) are commonly used for controlled drug release. The structure of these thin films is controlling the drug transport from the core to the surrounding liquid in the stomach or intestine. However, detailed understanding of the structure evolution is lacking. READ MORE

6. 4. Diffusion Controlled Drug Release from Slurry Formed, Porous, Organic and Clay-derived Pellets

   Author : Erik Jämstorp Berg; Maria Strømme; Håkan Engqvist; Susanne Bredenberg; Pentti Tengvall; Nanoteknologi och funktionella material Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffusion; Drug delivery; Antithrombotic drugs; Highly potent opioids; Modeling; Clays; Polymers; Pellets; Beads; Materialvetenskap; Materials Science;

   Abstract : Coronary artery disease and chronic pain are serious health issues that cause severe discomfort and suffering in society today. Antithrombotic agents and highly potent analgesics play a critical role in improving the recovery process for patients being treated for these diseases. READ MORE

7. 5. On enhancement of bone formation using local drug delivery systems

   Author : Ali Alenezi; Ann Wennerberg; Malmö universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone formation; local drug delivery systems;

   Abstract : Introduction: Despite that many reports have confirmed the long-term clinical success rates associated with implant treatment, implant failure to achieve and maintain osseointegration still occurs in many cases. Local and sustained drug release at the bone-implant interface is one of the strategies that have been suggested to improve the osseointegration. READ MORE