Search for dissertations about: "positivity effect"

Showing result 1 - 5 of 35 swedish dissertations containing the words positivity effect.

2. 1. Processing affective information after sleep loss

   Author : Andreas Gerhardsson; Håkan Fischer; Johanna Schwarz; Daniel Lundqvist; Philippe Peigneux; Stockholms universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sleep deprivation; sleep restriction; affective bias; emotional working memory; positivity effect; sömnbrist; sömnrestriktion; emotionellt bias; arbetsminne; positivitetseffekten; psykologi; Psychology;

   Abstract : It is not fully understood why we need to sleep, although it is evident that sleep loss has consequences for many emotional and cognitive functions. The last couple of decades, sleep researchers have been increasingly devoted to better understand the relationship between sleep and affect. READ MORE

4. 2. Pharmacokinetic, efficacy and safety modeling of new treatments against drug-resistant tuberculosis

   Author : Lénaïg Tanneau; Mats Karlsson; Elin Svensson; Italo Poggesi; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; pharmacometrics; nonlinear mixed effect models; tuberculosis; drug-resistance; bedaquiline; delamanid; metabolite; drug-drug interactions; QTc interval; transaminases; time-to-positivity; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Tuberculosis (TB) is an ancient infectious disease that remains one of the greatest killers on the planet. Its eradication is impeded by the development of resistance to first-line treatment. Each year half a million patients are infected with drug-resistant (DR) TB. READ MORE

5. 3. Modelling and Simulation to Improve Antimalarial Therapy

   Author : Jesmin Permala Lohy Das; Mats Karlsson; Martin Bergstrand; Joel Tarning; Mads Krielgaard; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; pharmacokinetics; pharmacodynamics; malaria; artemisinin; weekly dosing; resistant; pregnant populations; intermittent preventive therapy; parasite clearance; day 3 positivity; nomogram; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

   Abstract : The introduction of artemisinin-based combination therapy (ACT) substantially reduced malaria-related mortality and morbidity during the past decade. Despite the widespread use of ACT, there is still a considerable knowledge gap with regards to safety, efficacy and pharmacokinetic properties of these drugs, particularly in vulnerable populations like children and pregnant women. READ MORE

6. 4. Prognostic and predictive factors in Vietnamese breast cancer : a comparison with Swedish patients and effect on survival

   Author : Thang Vu Hong; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Breast cancer;

   Abstract : Breast cancer is a leading cause of cancer death among women in Western and Asian countries. Previous studies showed that Asian and African-American patients more often had poor tumor prognostic factors than Caucasian patients. There are however only few reports on tumor prognostic factors and survival in Vietnamese breast cancer patients. READ MORE

7. 5. Two novel combination therapies of glioblastoma multiforme from a Cx43 perspective : studies of in vitro models

   Author : Thomas Asklund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Glioma; gap junction; Cx43; bystander effect; HSV-tk; HDAC inhibitor; tyrosine kinase inhibitor;

   Abstract : The group of patients suffering from the malignant brain tumour glioblastoma multiforme (GBM) have a median survival of only about one year. Thus, new treatment strategies are urgently needed. Gap junctions are intercellular channels, permitting intercellular transfer of water soluble substances. READ MORE