Search for dissertations about: "post modification"

Showing result 1 - 5 of 166 swedish dissertations containing the words post modification.

  1. 1. Ribosomal RNA Modification Enzymes : Structural and functional studies of two methyltransferases for 23S rRNA modification in Escherichia coli

    Author : Avinash S. Punekar; Maria Selmer; Martino Bolognesi; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; ribosome biogenesis; ribosome assembly; ribosomal RNA; peptidyltransferase center; domain V; post-transcriptional modification; methyltransferases; S-adenosyl-methionine; RlmM; Cm2498; RlmJ; m6A2030; X-ray crystallography; substrate recognition; substrate specificity; catalytic mechanism; evolution; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biokemi; Biochemistry;

    Abstract : Escherichia coli ribosomal RNA (rRNA) is post-transcriptionally modified by site-specific enzymes. The role of most modifications is not known and little is known about how these enzymes recognize their target substrates. READ MORE

  2. 2. Study of the colonic mucus layer by mass spectrometry

    Author : Sjoerd van der Post; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MUC2; mucin; intestine; proteomics; mass spectrometry;

    Abstract : The mucus covering our internal mucosal surfaces is a part of the innate immune system, and the first line of defense against microbial challenges. The need of an efficient defense system is especially important in the lower parts of the digestive tract where the microbiota reaches its highest density. READ MORE

  3. 3. Modification of zeolites and synthesis of SAPO-templated carbon

    Author : Yunxiang Li; Niklas Hedin; Anders Palmqvist; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; microporous material; zeolite; SAPO templated carbon; hydrothermal synthesis; CVD; post modification; direct modification; snowflake; Materials Chemistry; materialkemi;

    Abstract : Zeolites are crystalline aluminosilicates with diverse structures and uniform porosities. They are widely used as catalysts, adsorbents and ion-exchangers in industry. Direct or post modifications optimize the performance of zeolites for different applications. In this thesis, IZM-2 and TON-type zeolites were synthesized, modified and studied. READ MORE

  4. 4. Structured molecular sieves : synthesis, modification and characterization

    Author : Valeri Naydenov; Luleå tekniska universitet; []

    Abstract : The work presented concerns synthesis of structured molecular sieves. The preparation procedure is based on the use of ion exchange resins as macrotemplates. Macroporous cation or anion exchange resin types were used depending on the molecular sieve type to be synthesized. READ MORE

  5. 5. Regulation of TGF-β Signaling by Post-Translational Modifications

    Author : Peter Lönn; Aristidis Moustakas; Carl-Henrik Heldin; Petra Knaus; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; TGF-β; Smad; PARP-1; PARG; ALK5; SIK; signal transduction; transcription; post-translational modification; phosphorylation; ubiquitin; ADP-ribosylation; DNA-binding; receptor degradation; Cell and molecular biology; Cell- och molekylärbiologi; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Transforming growth factor-β (TGF-β) signaling is initiated when the ligand binds to type II and type I serine/threonine kinase receptors at the cell surface. Activated TGF-β type I receptors phosphorylate R-Smads which relocate, together with co-Smads, to the cell nucleus and regulate transcription. READ MORE