Search for dissertations about: "post-mitotic"

Showing result 1 - 5 of 18 swedish dissertations containing the word post-mitotic.

  1. 1. Signaling pathways and novel genetic factors involved in modulation of cisplatin response in C. elegans

    Author : Dorota Raj; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C. elegans; cisplatin; cancer; stress; immunity; post-mitotic; tail-anchored proteins;

    Abstract : Cancer is a major cause of mortality throughout the world. Despite the effort of the scientific community, plenty remains to understand about the biology or genetics of cancer. In solid tumors often as many as 90-99% of all cells are non-dividing. READ MORE

  2. 2. Genetic mechanisms behind cell specification in the Drosophila CNS

    Author : Magnus Baumgardt; Stefan Thor; Angela Giangrande; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; nervous system development; cell specification; stem cells; cell proliferation; combinatorial coding; feedforward loop; Developmental biology; Utvecklingsbiologi;

    Abstract : The human central nervous system (CNS) contains a daunting number of cells and tremendous cellular diversity. A fundamental challenge of developmental neurobiology is to address the questions of how so many different types of neurons and glia can be generated at the precise time and place, making precisely the right connections. READ MORE

  3. 3. Free radicals in cellular pathology : Mechanisms behind lipofucin formation in cultured myocardial cells

    Author : Rasi Marzabadi Massoud; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Lipofuscin, or age pigment, may be defined as a yellowish-brown,autofluorescent, protein and lipid containing pigment that accumulates inthe lysosomal vacuome of a variety of post-mitotic cell types in man andanimals during aging. Lipofuscin is the end product of peroxidation,fragmentation and polymerization of proteins and lipids. READ MORE

  4. 4. Mechanisms controlling striatal projection neurone generation, from patterning to early differentiation

    Author : Håkan Toresson; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pbx; meis; sonic hedgehog; small eye; pax6; gsh2; gsh1; cerebral cortex; striatum; telencephalon; mutant; development; mouse; embryo; retinoic acid; Clinical biology; Klinisk biologi;

    Abstract : The striatum is part of the telencephalon, the most anterior part of the vertebrate brain. From when it first can be identified, telencephalic morphology is highly complex and a wide range of mechanisms has been suggested to participate in its induction, patterning and neurogenesis. READ MORE

  5. 5. From stem cell to neuron : A sox perspective

    Author : Maria Bergsland; Karolinska Institutet; Karolinska Institutet; []

    Abstract : The differentiation of stem cells into the more than 100 billion neurons that compose the central nervous system (CNS) is one of the most remarkable transformations during vertebrate development. A central problem of this process is how neural lineage selection initially is specified in pluripotent stem cells and maintained during the course of neurogenesis. READ MORE