Search for dissertations about: "post-mitotic"

Showing result 11 - 15 of 20 swedish dissertations containing the word post-mitotic.

  2. 11. Morphological and functional effects of insulin signaling and the bHLH transcription factor Dimmed on different neuron types in Drosophila

    Author : Yiting Liu; Dick R. Nässel; Irene Miguel-Aliaga; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; insulin signaling; Dimm; neuropeptide; insulin receptor; insulin-like peptide; drosophila; funktionell zoomorfologi; Functional Zoomorphology;

    Abstract : In Drosophila, the insulin signaling pathway is at the interface between dietary conditions and control of growth and development, reproduction, stress responses and life span. Eight insulin like peptides (Dilp1-8), an insulin tyrosine kinase receptor (dInR) and its downstream components, as well as a relaxin-like receptor type (Lgr3) form the core of this signaling. READ MORE

  4. 12. Single cell analysis of checkpoints in G1

    Author : Hanna-Stina Martinsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cell cycle; restriction point; cyclin D; pRb; rRNA synthesis; cell growth; attachment;

    Abstract : It is becoming evident that defective cell cycle regulation is an important property of the cancer cell. The restriction point (R), a G1 checkpoint after which cell cycle progression becomes independent of extracellular growth factors, is often aberrant in cancer cells. READ MORE

  5. 13. Protein Quality Control at the Inner Nuclear Membrane – The Asi complex in Saccharomyces cerevisiae

    Author : Marina Pantazopoulou; Per Ljungdahl; Jaspersen Sue; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; nuclear envelope; nuclear quality control NQC ; ubiquitin; proteasome; inner nuclear membrane-associated degradation INMAD ; Cell Biology; cellbiologi;

    Abstract : The nuclear envelope is a barrier comprised of outer and inner membranes that separate the cytoplasm from the nucleoplasm. The outer (ONM) and inner (INM) membranes have different physical characteristics and protein compositions. READ MORE

  6. 14. Understanding ageing : the role of mitochondria in determination of caenorhabditis elegans life span

    Author : Ivana Bratic Hench; Karolinska Institutet; Karolinska Institutet; []
    Keywords : C. elegans;

    Abstract : Mitochondria are organelles found in eukaryotic cells. They are involved in many vital cellular functions. Consequently, mitochondrial dysfunction leads to a variety of human disorders. Many studies of the last 50 years showed that mitochondria are involved in the regulation of physiological ageing. READ MORE

  7. 15. DNA fragility in the context of neural stem cell fate : a multi-method integrative exploration of genome dynamics

    Author : Roberto Ballarino; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Recent advances in mapping the complex genetic architecture underlying various debilitating brain disorders have enabled identification of several genetic risk variants. However, these risk variants only explain part of the heritability and vulnerability to these disorders in early development. READ MORE