Search for dissertations about: "post-mitotic"
Showing result 16 - 20 of 20 swedish dissertations containing the word post-mitotic.
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16. Molecular regulation and analysis of neural stem and cancer cell characteristics
Abstract : Every single cell within an organism is constantly facing the demanding task of preserving the integrity of its genomic material to secure proper function and clearance from disease. To accomplish this cells rely on DNA repair mechanisms that are well- conserved throughout evolution and highly specialized in removing particular types of DNA damage. READ MORE
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17. Modifying xenogeneic immune recognition and engraftment by genetic engineering
Abstract : Transplantation using xenogenic organs, tissues and cells (i.e. xenotransplantation) is a potential solution to the shortage of those from human sources. Vascular endothelial cells (ECs) are the most immediate barrier between the xenogeneic donor organ and the host defense systems. READ MORE
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18. Blue light induced retinal damage
Abstract : Visual perception results from a response to radiation between 400 and 760 mu reaching the retina. Photoreceptor cells are differentiated post-mitotic retinal neurons uniquely adapted for the efficient capture of photons and for the initiation of visual transduction. READ MORE
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19. Mechanisms controlling midbrain dopaminergic neuron development
Abstract : The degeneration of midbrain dopaminergic (mDA) neurons accounts for some of the main motor symptoms of Parkinson’s disease (PD). Efforts during the last decades have focused on understanding how mDA neurons are generated and maintained with the hope of developing novel stem cell-based replacement therapies. READ MORE
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20. Oxidative stress-related damage of retinal pigment epithelial cells : possible protective properties of autophagocytosed iron-binding proteins
Abstract : Oxidative stress is a major pathogenic factor in the development of age-related macular degeneration (AMD), which is the most common cause of severe central visual impairment in the elderly population in the western world.It is believed that the degenerative process starts in the retinal pigment epithelium (RPE). READ MORE